The Difference in the Biological Characteristic Characteristics of the Heart and Lung Meridians

NCT05690217 | Completed

• 1 other identifier: ZSLL-KY-2019-001
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The association between viscera and the body surface remains obscure, but a better understanding of it will maximize its diagnostic and therapeutic values in clinical practice. Therefore, this study aimed to investigate the specificity of the association between viscera and the body surface in the pathological state.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

acupuncture; meridians; biological characteristic

Outcome Measures

Primary Outcomes (3)

• Perfusion unit

  Perfusion unit of acupuncture points is measured by Laser doppler flowmetry

  Baseline

• Temperature

  Temperature of acupuncture points is measured by infrared thermography

  Baseline

• Regional oxygen saturation

  Regional oxygen saturation of acupuncture points is measured by functional near-infrared spectroscopy

  Baseline

Study Arms (2)

COPD group

There are 40 chronic obstructive pulmonary disease (COPD) patients in the COPD group.

Healthy control group

There are 40 age-matched healthy participants in the healthy control group.

Eligibility Criteria

• Age: 20 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The diagnostic criteria of COPD were based on criteria proposed by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) consensus published in 2017, in which persistent airflow obstruction is confirmed according to the pulmonary function test. Healthy participants were determined by a medical examination report within 6 preceding months for confirming their health conditions.

You may qualify if:

• COPD participants were eligible if they 1) satisfied the diagnostic criteria of COPD; 2) were in the stable phase of COPD; 3) were 20 ≤ age ≤ 75 years; 4) fully understood the study protocol and signed the written informed consent. Healthy participants were eligible if they 1) were healthy subjects who provided a medical examination report within 6 preceding months for confirming their health conditions; 2) were age-matched with the COPD group; 3) fully understood the study protocol and signed the written informed consent.

You may not qualify if:

• COPD patients were excluded if they 1) had other major lung diseases, such as bronchiectasis, pneumothorax, and lung tumors; 2) had concomitant heart diseases; 3) had serious concomitant diseases in major systems that were not controlled effectively 4) had mental diseases, history of drug abuse, and alcohol dependence; 5) were lactating or pregnant and 6)had scarring, hyperpigmentation, redness, swelling and heat in the skin around the measurement sites, which would affect the accuracy of examinations. Healthy subjects were excluded if they 1) had mental illness, history of drug abuse and alcohol dependence; 2) were lactating or pregnant; 3) had scarring, hyperpigmentation, redness, swelling, and heat in the skin around the measurement sites, which would affect the accuracy of examinations.

Sponsors & Collaborators

• The Third Affiliated hospital of Zhejiang Chinese Medical University: lead

Study Sites (1)

the Third Affiliated Hospital of Zhejiang Chinese Medical University

Hangzhou, Zhejiang, 310000, China

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Jianqiao Fang, Ph.D

  The Third Affiliated hospital of Zhejiang Chinese Medical University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Attending doctor

Study Record Dates

• First Submitted: January 10, 2023
• First Posted: January 19, 2023
• Study Start: January 1, 2019
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: January 19, 2023

Record last verified: 2023-01

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)