NCT05689515

Brief Summary

A small pilot study to assess feasibility and acceptability of the PL4Y intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 9, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 19, 2023

Completed
14 days until next milestone

Study Start

First participant enrolled

February 2, 2023

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2025

Completed
Last Updated

February 4, 2025

Status Verified

February 1, 2025

Enrollment Period

2 years

First QC Date

January 9, 2023

Last Update Submit

February 3, 2025

Conditions

Keywords

Positive LinksYouthEmerging Adults

Outcome Measures

Primary Outcomes (2)

  • Completion of Feasibility Survey

    Feasibility survey completion by participants regarding usability of the PL4Y intervention

    12 months

  • Viral plasma load measurement

    Virologic suppression is the primary goal of HIV treatment. Virologic failure is defined as a measurement over 200 copies per mL by the Department of Health and Human Services, and is the primary determinant of successful HIV control.

    12 months

Study Arms (2)

Mobile Health App group

EXPERIMENTAL

Mobile health app to increase rates of engagement in care in youths living with HIV

Behavioral: Mobile health app

Control group

NO INTERVENTION

Standard of care for youths living with HIV

Interventions

A mobile app provided to participants to assess effectiveness in managing HIV

Also known as: PL4Y
Mobile Health App group

Eligibility Criteria

Age18 Years - 29 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Confirmed HIV infection
  • Recent diagnosis of HIV (within the past 6 months) OR be virologically unsuppressed (\>1000 copies/ml) OR disengaged from HIV care (\< 2 visits/last 12 months \> 90 days apart)

You may not qualify if:

  • Cannot consent
  • Unwilling to come to visits
  • Unwilling to be in San Antonio for a year

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Health Center Downtown

San Antonio, Texas, 78207, United States

Location

MeSH Terms

Conditions

HIV Seropositivity

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Officials

  • Barbara Taylor, MD, MS

    University of Texas Health Science Center San Antonio

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Participants will be randomized in a 2:1 ratio to intervention (PL4Y use) or standard of care
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 9, 2023

First Posted

January 19, 2023

Study Start

February 2, 2023

Primary Completion

January 30, 2025

Study Completion

January 30, 2025

Last Updated

February 4, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will share

The research team will compose a manuscript including data on preliminary efficacy of the PL4Y program in YLWH with regards to virologic suppression, retention in care, stigma, self-efficacy, and social support. The study team will also have a detailed guide to operating procedures, including successful recruitment and retention techniques and study processes such as teching tarticipants how to use PL4Y and monitoring the community message board. All data regarding participants will be shared as de-identified data.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
At study completion and when all data have been analyzed to publish in a peer reviewed journal.

Locations