The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties

NCT05688527 | Unknown

• 1 other identifier: ARB_SKIN5
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes. The 5 facial products in the regimen are a cleansing balm, a toner, a serum, a moisturizer. and an eye cream.

Conditions

Wrinkle

Outcome Measures

Primary Outcomes (2)

• Appearance of facial wrinkles

  Change in wrinkle severity measured by photographic analysis (BTBP 3D Camera System)

  8 weeks

• Change in skin pigmentation in the undereye area

  Change in skin pigmentation in the undereye area by Skin colorimetric analysis of pigment

  8 weeks

Secondary Outcomes (19)

• Skin hydration

  1 week

• Skin hydration

  4 weeks

• Skin hydration

  8 weeks

• Transepidermal water loss

  1 week

• Transepidermal water loss

  4 weeks

Study Arms (1)

5 Step Skin Care Regimen

EXPERIMENTAL

The subject uses 5 facial products in the regimen; a cleansing balm, a toner, a serum, a moisturizer and an eye cream.

Other: Cleansing Balm; Other: Toning Essence; Other: Facial Serum; Other: Moisturizer; Other: Eye Cream

Interventions

Cleansing Balm OTHER

DermResults Cleansing Balm w/ Avocado Oil twice daily

5 Step Skin Care Regimen

Toning Essence OTHER

DermResults Advanced Toning Essence w/ Mineral Booster twice daily

5 Step Skin Care Regimen

Facial Serum OTHER

DermResults Advanced Serum w/ Hyaluronic Acid twice daily

5 Step Skin Care Regimen

Moisturizer OTHER

DermResults Advanced Moisturizer w/ Hyaluronic Acid twice daily

5 Step Skin Care Regimen

Eye Cream OTHER

DermResults Advanced Eye Cream w/ Hyaluronic Acid twice daily

5 Step Skin Care Regimen

Eligibility Criteria

• Age: 35 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Men and women between the ages of 35 years old and 65 years old.
• Must have fine lines and wrinkles around the eyes.

You may not qualify if:

• Individuals who are pregnant or breastfeeding.
• Prisoners
• Adults unable to consent
• Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
• Subjects using any topical retinoid, hydroquinone, kojic acid, bakuchiol, hyaluronic acid or benzoyl peroxide containing topical product within 2 weeks of starting study or any subject unwilling to refrain from washout prior to enrollment.
• Subjects with any facial treatments in the past 6 months and who are unwilling to withhold facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, tightening treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin.
• Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.

Sponsors & Collaborators

• Integrative Skin Science and Research: lead
• Arbonne: collaborator

Study Sites (1)

Integrative Skin Science and Research

Sacramento, California, 95815, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 5, 2023
• First Posted: January 18, 2023
• Study Start: January 23, 2023
• Primary Completion: May 16, 2023
• Study Completion: December 16, 2023
• Last Updated: July 25, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)