NCT05688358

Brief Summary

  1. 1.This study aims to determine the serum levels of interleukin-17A (IL-17A) in children with juvenile idiopathic arthritis (JIA)
  2. 2.Analyze the correlation between IL-17A values and disease activity, certain clinical features, and laboratory markers of inflammation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
78

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2023

Typical duration for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 7, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

January 18, 2023

Completed
14 days until next milestone

Study Start

First participant enrolled

February 1, 2023

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2025

Completed
Last Updated

January 18, 2023

Status Verified

January 1, 2023

Enrollment Period

2.2 years

First QC Date

January 7, 2023

Last Update Submit

January 15, 2023

Conditions

JIA

Outcome Measures

Primary Outcomes (1)

  • Serum Interleukin - 17A in juvenile idiopathic Arthritis

    This study aims to determine the serum levels of interleukin-17A (IL-17A) in children with juvenile idiopathic arthritis (JIA) -Analyze the correlation between IL-17A values and disease activity, certain clinical features, and laboratory markers of inflammation

    baseline

Interventions

serum levels of interleukin-17A in JIADIAGNOSTIC_TEST

IL17 A by Enzyme linked immunosorbent assay method

Eligibility Criteria

AgeUp to 16 Years
Sexall
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Patients less than 16 years at onset of disease and diagnosed with oligoarticular and polyarticular JIA, fulfilling the ILAR classificationcriteria of JIA.

You may qualify if:

  • Control group will include age-and-sex-matched apparently healthy children.

You may not qualify if:

  • Patients with diabetes mellitus, acute or chronic infections.
  • Patients with another causes of arthritis other than JIA.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

Central Study Contacts

Mennat-Allah Khaled Tolba Abdelraheem, master

CONTACT

0201093579968menna.k.tolba@gmail.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident doctor

Study Record Dates

First Submitted

January 7, 2023

First Posted

January 18, 2023

Study Start

February 1, 2023

Primary Completion

May 1, 2025

Study Completion

September 1, 2025

Last Updated

January 18, 2023

Record last verified: 2023-01