The Improvement of Black Raspberry in Obese and Mild AZ Patients Infected With H. Pylori
BR
1 other identifier
interventional
21
1 country
1
Brief Summary
The current study was designed to check the impact of black raspberry (BR) on obese and mild Alzheimers (AZ) patients infected with Helicobacter pylori (H pylori). Through checking various parameters including anthropometric, antioxidants, and CDR.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable alzheimer-disease
Started Nov 2021
Shorter than P25 for not_applicable alzheimer-disease
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 11, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 5, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
August 4, 2022
CompletedFirst Submitted
Initial submission to the registry
December 7, 2022
CompletedFirst Posted
Study publicly available on registry
January 11, 2023
CompletedJanuary 11, 2023
December 1, 2022
7 months
December 7, 2022
December 23, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Glycemic indices
No significant changes in any of the glycemic indices
8 weeks
Anthropometric parameters
BMI were significantly altered
8 weeks
Study Arms (2)
BR group
EXPERIMENTALExperimental group AZ subjects were requested to take 50 g of BR powder dissolved in 240 ml of water for 4 weeks.
Placebo group
PLACEBO COMPARATORPlacebo group AZ subjects were requested to take 50 g of dextrin powder dissolved in 240 ml of water for 4 weeks.
Interventions
Experimental group subjects were requested to take 50 g of Black Raspberry powder for 4 weeks.
Eligibility Criteria
You may qualify if:
- BMI ≧ 27, Waist circumference: men ≧ 90cm, women ≧ 80cm,
- Body fat: male ≧ 25%, female ≧ 30%,
- UBT 13C test value\> 10‰ (H. pylori (+)),
- CDR (clinical dementia rating) = 0.5
You may not qualify if:
- BMI\< 27
- Severe chronic diseases (liver disease, cardiovascular disease, kidney disease)
- Alcohol abuse
- Smoking habit
- Taking berry-related supplementation or any known allergies related to berries.
- Subjects with prior history of H. pylori infection were treated with triple therapy.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chung Shan Medical University
Taichung, Taichung, 40201, Taiwan
Related Publications (1)
Tandoro Y, Chiu HF, Tan CL, Hsieh MH, Huang YW, Yu J, Wang LS, Chan CH, Wang CK. Black raspberry supplementation on overweight and Helicobacter pylori infected mild dementia patients a pilot study. NPJ Sci Food. 2025 Feb 12;9(1):9. doi: 10.1038/s41538-024-00356-w.
PMID: 39939643DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Chin-Kun Wang, Ph.D
Chung Shan Medical University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
December 7, 2022
First Posted
January 11, 2023
Study Start
November 11, 2021
Primary Completion
June 5, 2022
Study Completion
August 4, 2022
Last Updated
January 11, 2023
Record last verified: 2022-12
Data Sharing
- IPD Sharing
- Will not share