Evaluation of Visual Parameters by Visual Evoked Potentials Captured by EEG

NCT05675852 | Unknown

• 1 other identifier: 2017%244
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This project will be based on an approach that has already proven itself in the field of the development of low-level visual functions such as visual acuity, vernier acuity and contrast sensitivity (Norcia \& Tyler, 1985): scanning visual evoked potentials" (sVEP), a special case of steady-state visual evoked potentials (SSVEP). While SSVEPs consist of presenting a visual stimulus periodically, sVEPs are SSVEPs where the value of a parameter (e.g. the contrast of the stimulus) varies. This variation ("scanning") makes it possible to determine the threshold value where an electroencephalographic (EEG) response is perceived, and thus to evaluate visual parameters such as visual acuity, vernier acuity and contrast sensitivity. In this study we therefore record the amplitude of the EEG electrical signal during the presentation of low-level stimuli such as spatial frequency gratings or increasing or decreasing contrast.

Conditions

Visual Neurosciences

Outcome Measures

Primary Outcomes (1)

• Threshold of visual recognition of low and high grade visual stimuli

  Fast periodic visual stimulation using stimuli such as gratings, checkerboards, words and faces

  4 months

Study Arms (1)

Healthy participants

Healthy participants aged from 1 to 75 years old. All experiments conducted in this study will make use of the electroencephalogram (EEG) recording technique. Healthy participants cannot participate if they suffer from dermatosis on the scalp. There is no other contraindication to the practice of an EEG, which simply consists of recording the electrical activity of the brain on a trace, after application of a conductive gel on the scalp where sensors connected to a recording device are placed. We will collect the cerebral electrical response by the technique of steady state visual evoked potentials (SSVEP) which consists of presenting a visual stimulus periodically to interpret the EEG signal according to those variations.

Other: 68-electrode electroencephalography with steady state visual evoked potentials

Interventions

68-electrode electroencephalography with steady state visual evoked potentials OTHER

Electroencephalography is registered through a 68-electrode electroencephalography while stimuli will be presented at the centre of the screen at a distance of 150cm. The pattern of visual stimulation is based on the technique of steady state visual evoked potentials. These potentials consist of the presentation of a visual stimulus at a (relatively fast) periodic rate to produce an EEG signal over the occipital cortex exactly at the frequency of stimulation. By varying the value of a parameter of the stimulation (e.g. the contrast of the stimulus) varies. This variation makes it possible to determine the threshold value where an EEG response is perceived, and thus to evaluate visual parameters such as visual acuity, contrast sensitivity or recognition of more complex shapes.

Healthy participants

Eligibility Criteria

• Age: 1 Year - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Healthy participants to better understand visual neurosciences.

You may qualify if:

• Absence of ocular pathologies except for refractive errors
• Absence of neurologic conditions

You may not qualify if:

• Participants using neurologic or psychiatric drugs
• Scalp pathology

Sponsors & Collaborators

• Université Catholique de Louvain: lead

Study Sites (1)

Institute Of NeuroSciences

Woluwe-Saint-Lambert, Brussels Capital, 1200, Belgium

RECRUITING

Central Study Contacts

Demet Yuksel

CONTACT

+32 (2) 764 21 48; demet.yuksel@saintluc.uclouvain.be

Coralie Hemptinne

CONTACT

+32 (2) 764 1969; coralie.hemptinne@saintluc.uclouvain.be

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 3, 2023
• First Posted: January 9, 2023
• Study Start: December 1, 2022
• Primary Completion: January 1, 2023
• Study Completion: April 1, 2023
• Last Updated: January 9, 2023

Record last verified: 2023-01

Data Sharing

• IPD Sharing: Will not share

Locations

BE (1)