Effects Of Propofol-Dexmedetomıdıne And Propofol- Remıfentanıl In Hysteroscopıc Operations.
1 other identifier
observational
2
1 country
1
Brief Summary
In our study, the investigators aimed to compare the effects of dexmedetomidine-propofol and remifentanil-propofol combinations on perioperative spontaneous respiration, hemodynamics, recovery, participants, surgeon and anesthetist satisfaction in hysteroscopy, which is one of the ambulatory surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Jun 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 17, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
July 15, 2022
CompletedFirst Submitted
Initial submission to the registry
December 7, 2022
CompletedFirst Posted
Study publicly available on registry
January 6, 2023
CompletedJanuary 6, 2023
December 1, 2022
2 months
December 7, 2022
December 29, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
SEDATİON
RAMSEY SEDATİON SKORE \> 4 TİME (MİNUTE)
through study completion, an average of 1 year
RECOVERY
MODIFIED ALDRETE SCORE\>9 (MİNUTE)
through study completion, an average of 1 year
DESATURATION DESATURATION
SATURATION SATURATION RATIOS (%)
DURING THE SURGERY
RESPİRATORY RATE
RESPİRATORY RATE (.../MİNUTE)
DURING THE SURGERY
END-TİDAL CO2
END-TİDAL CO2 (mmHg)
DURING THE SURGERY
INTEGRATED PULMONARY INDEX
INTEGRATED PULMONARY INDEX (1-10)
DURING THE SURGERY
Secondary Outcomes (3)
HEART RATE
DURING THE SURGERY
NON INVASIVE SYSTOLİC AND BLOOD PRESSURE
DURING THE SURGERY
NON INVASIVE DİASTOLİC BLOOD PRESSURE
DURING THE SURGERY
Study Arms (2)
Group DP
Propofol (Dexmedetomidine (Sedadomide 200 µg/2 ml, KOÇAK FARMA Turkey) 1mcg/kg bolus was administered to Group DP in 10 minutes, then 0.2-1.4 mcg/kg/hour infusion dose was started.-®Lipuro 1%(10 mg/ml), B. Braun Indonesia ) 1mg/kg bolus was administered.
Group RP
Propofol (Propofol-®Lipuro 1%(10 mg/ml), B. Braun Indonesia ) 1mg/kg bolus was administered, After a 0.25mcg/kg bolus of Remifentanil (Ultiva®, GlaxoSmithKline, Belgium) was administered to Group RP, a 0.025-0.1mcg/kg/minute infusion dose was started.
Interventions
Propofol-Dexmedetomidine AND Propofol-Remifentanil
Eligibility Criteria
This study was conducted prospectively after the approval of Van Yüzüncü Yıl University Ethics Committee. A total of 80 patients in 2 groups of 40 ASA I-II, aged 18-65 years were included in the study.
You may qualify if:
- AGE 18-65 ASA I AND II
You may not qualify if:
- OTHERS
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Siirt Training and Research Hospitallead
- Yuzuncu Yil Universitycollaborator
Study Sites (1)
Siirt Eğitim Ve Araştirma Hastanesi
Siirt, Turkey (Türkiye)
Related Publications (1)
Oguz AK, Soyalp C, Tuncdemir YE, Tekeli AE, Yuzkat N. Sedoanalgesia with dexmedetomidine in daily anesthesia practices: a prospective randomized controlled trial. BMC Anesthesiol. 2025 Jan 29;25(1):45. doi: 10.1186/s12871-025-02918-1.
PMID: 39881245DERIVED
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- OTHER
- Target Duration
- 1 Day
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- medical doctor
Study Record Dates
First Submitted
December 7, 2022
First Posted
January 6, 2023
Study Start
June 17, 2021
Primary Completion
August 1, 2021
Study Completion
July 15, 2022
Last Updated
January 6, 2023
Record last verified: 2022-12