Glaucoma Assessment Via Reading Ability

NCT05673954 | Unknown

• 1 other identifier: IRB00006761-M2022800
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

To explore a quantitative glaucoma evaluation tool of glaucoma through the dynamic evaluation of reading ability based on logarithmic Chinese reading acuity chart (C-READ), and investigate its feasibility.

Conditions

Glaucoma, Primary Open Angle

Outcome Measures

Primary Outcomes (1)

• The Relationship between Reading Ability and C-READ Test Results

  The Relationship between Reading Ability and C-READ Test Results

  January 2023 to December 2023

Study Arms (2)

Case group

Patients with primary open angle glaucoma

Diagnostic Test: C-Read test

Control group

Healthy people

Diagnostic Test: C-Read test

Interventions

C-Read test DIAGNOSTIC_TEST

C-Read is a reliable and valid clinical tool for quantitatively testing the reading ability of readers of simplified Chinese characters.

Case group; Control group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The patients who were diagnosed as primary open angle glaucoma in the Eye Center of the Third Hospital of Beijing Medical University from January 2023 to December 2023 will be included. At the same time, healthy people will be included as the control group.

You may qualify if:

• Primary open angle glaucoma in at least 1 eye or labelled as a glaucoma suspect by a glaucoma specialist
• Age ≥18 years old
• with open angles on gonioscopy
• best-corrected visual acuity ≥0.5
• spherical refraction within ±5.0 diopters (D), and/or cylinder correction within 3.0 D

You may not qualify if:

• eyes with any evidence of physical abnormality of the iris or pupils on slit-lamp examination
• eyes with a history of trauma or inflammation
• undergone an intraocular surgery or laser within the previous 6 months/except uncomplicated cataract surgery
• using systemic or topical medications that could affect pupil responses, including pilocarpine or atropine
• presence of any media opacities that prevented good quality OCT or fundus images
• presence of any retinal or neurological disease other than glaucoma
• abnormal ocular motility that prevents binocular fixation (eg, nystagmus, strabismus)
• with severe systemic diseases or psychiatric disorders

Sponsors & Collaborators

• Peking University: lead

MeSH Terms

Conditions

Glaucoma, Open-Angle

Condition Hierarchy (Ancestors)

Glaucoma; Ocular Hypertension; Eye Diseases

Central Study Contacts

Chun Zhang

CONTACT

18301031059; zhangc1@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 30, 2022
• First Posted: January 6, 2023
• Study Start: January 1, 2023
• Primary Completion: December 31, 2023
• Study Completion: February 29, 2024
• Last Updated: January 6, 2023

Record last verified: 2022-12