"InMotion" - Physical Training With Creative Movement as an Intervention for Adults With Schizophrenia

NCT05673941 | Unknown

• 1 other identifier: 278241
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 2

Brief Summary

InMotion is a randomized controlled study where adults with schizophrenia and schizophrenia-similar conditions, will be recruited to receive physical training with creative movements as an intervention, twice a week for a period of 12 weeks. The main outcome is changes in schizophrenia-related symptoms, secondary outcomes are changes in quality of life, physical and cognitive function, brain activity, and how the intervention is experienced by the participants.

Conditions

Schizophrenia and Related Disorders

Keywords

Schizophrenia; Physical activity; Randomized trial; EEG; fNIRS; Motion capture; Dance; Creative movement; Physical Training

Outcome Measures

Primary Outcomes (1)

• Positive and Negative Syndrome Scale (PANSS)

  The Positive and Negative Syndrome Scale (PANSS) is an established psychiatric rating system that is an operationalized, drug-sensitive instrument that offers balanced representation of positive and negative symptoms and estimates their relationship to one another and to global (or general) psychopathology.

  45 minutes

Secondary Outcomes (16)

• Clinical Global Impression - Severity scale (CGI-S)

  2.5 minutes

• Clinical Global Impression - Improvement scale (CGI-I)

  2.5 minutes

• The Calgary Depression Scale for Schizophrenics (CDSS)

  10 minutes

• Body Awareness Questionnaire (BAQ-sv)

  10 minutes

• The personal and social performance scale (PSP)

  10 minutes

Study Arms (2)

Creative movement

EXPERIMENTAL

The intervention will be performed as a group activity twice a week during a 12-week period. Each group will include 4-6 participants under the guidance of two instructors, and a related party if needed or wanted from the participant. The exercise is partly accompanied with calm music and recorded nature sounds and partly made in silence listening to one's own bodily rhythm. The exercise consists of tasks related to cardio and strength training, balance, conscious breathing, body awareness, mental imagery (nature visualizations), flexibility, emotional expression, and movement anticipation together with the facilitator and fellow participants. All the tasks are practiced during a flow of 45- to 60-minute exercise without any major breaks. Complexity and physical intensity of the tasks will gradually increase over the 12-week intervention period.

Other: Creative physical training

Control group

NO INTERVENTION

The control group receives standard medical care and gets access to the intervention in digital form after the study has ended.

Interventions

Creative physical training OTHER

The intervention will be performed as a group activity twice a week during a 12-week period. Each group will include 4-6 participants under the guidance of two instructors, and a related party if needed or wanted from the participant. The exercise is partly accompanied with calm music and recorded nature sounds and partly made in silence listening to one's own bodily rhythm. The exercise consists of tasks related to cardio and strength training, balance, conscious breathing, body awareness, mental imagery (nature visualizations), flexibility, emotional expression, and movement anticipation together with the facilitator and fellow participants. All the tasks are practiced during a flow of 45- to 60-minute exercise without any major breaks. Complexity and physical intensity of the tasks will gradually increase over the 12-week intervention period.

Creative movement

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Schizophrenia diagnosis or schizophrenia similar condition, age 18-65 years, performing physical activity less than 150 min/week.

You may not qualify if:

• Current or recent history of substance abuse, bipolar disorder, severe autism, suicidal, severe physical illness, inability to read and understand the Swedish language and inability to interact with other people in a group.

Sponsors & Collaborators

• Örebro University, Sweden: lead

Study Sites (2)

Region Örebro county

Örebro, S-70185, Sweden

Location

Örebro University

Örebro, Sweden

Location

Related Publications (1)

• Poikonen H, Duberg A, Eriksson M, Eriksson-Crommert M, Lund M, Moller M, Msghina M. "InMotion"-Mixed physical exercise program with creative movement as an intervention for adults with schizophrenia: study protocol for a randomized controlled trial. Front Hum Neurosci. 2023 Jul 5;17:1192729. doi: 10.3389/fnhum.2023.1192729. eCollection 2023.

  PMID: 37476005 DERIVED

MeSH Terms

Conditions

Schizophrenia; Motor Activity

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders; Behavior

Study Officials

• Mats Eriksson, Professor

  Örebro University, Sweden

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: Participants will be pseudonymized by using a study code. The researchers will be blind to group allocation when analyzing data.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 30, 2022
• First Posted: January 6, 2023
• Study Start: September 1, 2022
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2025
• Last Updated: January 6, 2023

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

SE (2)