Factors Affecting Prognosis of Open Globe Injuries

NCT05663814 | Unknown

• 1 other identifier: Open globe injuries
• Study Type: observational
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

: Detailed history should be taken from the patients ( age ,sex ,location of accident (rural or civil) , time of injury , mode of trauma, exact mechanism of injury ) Examination at baseline to determine location and extent of injury. Associated injuries e.g. cataract ,hyphema . Assessment for other life threatening injuries. Exclusion of IOFB. The presenting visual acuity should be recorded in injuried and uninjuried eye. Fundus examination if possible. The pupils should be examined for RAPD (in blunt trauma searching post traumatic optic neuropathy) Slit lamp examination at presentation to detect extent of damage. {type of wound ( corneal ,scleral ,or corneoscleral ) , prolapsed uveal tissue presence of hyphema ,sublaxated or dislocated lens ,prolapsed vitreous } Investigations done before repair (e.g. CT orbit ) Time of primary repair should be recorded. Follow up visits at 1 day, 1 week, 1 month, 3 months for :-

1. 1.For healing.
2. 2.Suture status.
3. 3.Detailed slit lamp and fundus examination.
4. 4.UCVA
5. 5.BCVA
6. 6.Investigations including:- B scan if hazy media OCT if clear media
7. 7.Refraction if possible Post operative complications and 2ry interventions

Conditions

Open Globe Injury

Outcome Measures

Primary Outcomes (1)

• Factors affecting prognosis of open globe injuries in Assiut university hospitals

  Final visual acuity in Snellen chart

  1 year

Eligibility Criteria

• Age: 6 Years+
• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Any patient more than 6 years presented with open globe injury

You may qualify if:

• Age + 6
• Laceration, incised injury ,Penetrating and perforating injuries
• Rupture globe

You may not qualify if:

• age less than 6
• patients unwilling to participate in study
• patients with disorganized globes

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Zhou Y, Chang P, Abdelmalik B, Mayer Z, Shah A, Steigleman WA. Prognosis of Open Globe Injuries at a Tertiary Referral Center: The Modified Florida Ocular Trauma Score. Am J Ophthalmol. 2022 Dec;244:152-165. doi: 10.1016/j.ajo.2022.08.015. Epub 2022 Aug 23.

  PMID: 36007553 BACKGROUND

Study Officials

• Kamel Soliman, Prof

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed Natag

CONTACT

00201115872699; Mohammedali.natag@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: November 19, 2022
• First Posted: December 23, 2022
• Study Start: December 1, 2023
• Primary Completion: October 1, 2024
• Study Completion: December 30, 2024
• Last Updated: December 23, 2022

Record last verified: 2022-12