NCT05660733|Recruiting
Study of the Aortic and Large Arterial Vessel Infections
Repia
French Registry Studying the Characteristics and Prognosis of Aortic and Large Arterial Vessel Infections
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Repia
French Registry Studying the Characteristics and Prognosis of Aortic and Large Arterial Vessel Infections
Sponsor study identifier
observational
500
1 country
1
Study Start
June 30, 2023
Actual (reported)Primary Completion
January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Aortic or large arterial vessel infections are rare but serious infections. Their management is based on French and American expert opinions. The quality of evidence supporting these guidelines is low because most publications on the subject correspond to case series and few interventional studies have been performed to validate their management. However, referral centres for vascular surgery are frequently solicited to give their opinion on patients suffering from mycotic aneurysms. In addition, the last few decades have seen the improvement of vascular surgery techniques allowing the management of more and more patients, often elderly and comorbid. There has therefore been an increase in the incidence of infectious complications associated with this care. It is therefore essential to participate in research on aortic and large arterial vessel infections. For this, a monocentric cohort study seems to be an essential first step to better understand the polymorphism and complexity of these patients.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 7, 2022
Actual (reported)December 21, 2022
Actual (reported)June 30, 2023
Actual (reported)January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
one-year mortality
Study of all-cause mortality in patients with aortic vascular infection and large arterial vessels during the first year of follow-up after diagnosis.
one year after the diagnosis
Identification of prognostic factors associated with arterial vascular infections
at the time of diagnosis and up to one year afterwards
All adults patients with proved aortic or large arterial vessel infection and without exclusion criteria.
Université de Lorraine, CHRU Nancy and APEMAC
Vandœuvre-lès-Nancy, Lorraine, 54511, France
Lalevee L, Serguei M, Jeanbert E, Simon M, Luc A, Settembre N, Henard S, Novy E, Guerci P, Lefevre B. Characteristics and outcomes of patients with infective native aortic aneurysm or vascular graft and endograft infection. Infect Dis (Lond). 2025 Oct;57(10):920-932. doi: 10.1080/23744235.2025.2502826. Epub 2025 May 16.
Lefèvre Benjamin, M.D.
Université de Lorraine & CHRU de Nancy
First Submitted
December 7, 2022
First Posted
December 21, 2022
Study Start
June 30, 2023
Actual (reported)Primary Completion
January 1, 2027
EstimatedDual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture
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Planned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
January 1, 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
August 8, 2025
Record last verified: 2025-08
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