NCT05658328

Brief Summary

The Sharing History through Active Reminiscence and Photo-imagery (SHARP) Program engages triads (primary caregiver, person living with dementia, caregiver support person) in walking and social reminiscence, using a group tablet to access routes and historical neighborhood images serving as conversational prompts. Focus is on adapting the SHARP model to older Black dementia caregivers and on caregiver physical and mental health. Study technology measures sleep and daily step count. Weekly online surveys assess health status. Pre-post assessments measure cognitive function and mental health. Focus groups assess adaptation needs, feasibility and acceptance, and cultural significance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 11, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

December 20, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

March 1, 2023

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 20, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 20, 2024

Completed
Last Updated

October 24, 2025

Status Verified

October 1, 2025

Enrollment Period

1.6 years

First QC Date

November 11, 2022

Last Update Submit

October 22, 2025

Conditions

Keywords

physical activityreminiscencesocial engagementdementia caregiverneighborhood-basedwalkingtechnology-enabledsleepgeriatric depressioncaregiver burdenAfrican American

Outcome Measures

Primary Outcomes (3)

  • Effect on sleep health

    Primary caregivers (and optionally PLWD) continuously wear an actigraphy watch for the study duration. The watch (Withings) measures heart rate variability, step-activity levels, sleep times, and sleep disturbances. Step counts (watch), total sleep time and quality (bed-mat sleep sensor), and HRV (watch and sleep sensor) will be analyzed using generalized mixed effects models with outcome being each incidence of occurrence (e.g., blue mood) or continuous outcomes (e.g., daily duration of sleep) and a time\*group interaction term.

    16 weeks

  • Effect on sleep health

    Primary caregivers (and optionally PLWD) use an under-the-mattress sleep sensor that measures sleep time and quality, HRV, and movement activity. Step counts (watch), total sleep time and quality (bed-mat sleep sensor), and HRV (watch and sleep sensor) will be analyzed using generalized mixed effects models with outcome being each incidence of occurrence (e.g., blue mood) or continuous outcomes (e.g., daily duration of sleep) and a time\*group interaction term.

    16 weeks

  • Change in blood pressure

    Pre-post difference in blood pressure are compared between primary caregivers in the experimental (SHARP intervention) and control groups (i.e., control (usual behavior) group waits 4 months then walks 4 months). Linear regression models with the primary and secondary outcome (BP and ZBI-12 (1°), at month 4 will be regressed on the baseline score of each outcome, the treatment group (experimental vs. control groups), controlling for caregiver age. The coefficient of the treatment group variable indicates the efficacy of the experiment.

    16 weeks

Secondary Outcomes (1)

  • Effect on mental health

    16 weeks

Other Outcomes (1)

  • Design effectiveness

    16 weeks

Study Arms (2)

Intervention Group

EXPERIMENTAL

Caregivers (MCI or healthy) randomized into this group walk 3x/week for 16 weeks with their care-partner (person living with early-stage dementia - PLWD) and their caregiver support person (MCI or healthy). Caregivers (and optionally for PLWD), wears an actigraphy watch, uses an under-the-mattress sleep sensor, and on a weekly basis completes weight and a health update survey. Mid- and end-study focus groups evaluate program effectiveness and needed adaptations.

Behavioral: SHARP - Physical and social activity

Waitlist Control

ACTIVE COMPARATOR

Caregivers (MCI or healthy) randomized into this group first complete baseline measures for 16 weeks, consisting of wearing an actigraphy watch, using an under-the-mattress sleep sensor, and, on a weekly basis, completing weight and a health update survey. These baseline measures are optional for PLWD. After 16 weeks of baseline data collection, the primary caregiver continues these measures while walking 3x/week for 16 weeks with their triad. The PLWD optionally completes measures and optionally wears the watch and sleep sensor. Mid- and end-study focus groups during the walking phase evaluate program effectiveness and needed adaptations.

Behavioral: SHARP - Physical and social activity

Interventions

Technology-enabled neighborhood walking 3x/week for 16 weeks with conversational reminiscence

Intervention GroupWaitlist Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Self-identified African American (caregiver and PWD)
  • Caregivers and PWD Age \> 55 years old; caregiver support person aged \>18 years old
  • Caregiver and PWD reside or resided for \>10 years in Portland's historically Black neighborhoods (to be familiar with Memory Markers about this area)
  • Able to ambulate independently for at least 45 minutes without the use of mobility aids
  • Meeting Cognition Criteria
  • a. Participants with MCI or early-stage/mild dementia will meet criteria consistent with those defined by Jak et al. and with the criteria outlined by the NIA-Alzheimer's Association workgroup
  • Cognitive function allows independent (or minimally assisted) travel to and from walk locations
  • Caregivers must have in-home reliable broadband internet (for weekly online surveys).
  • Ability to read, speak, and understand English - all participants
  • In general good health for their age (e.g., stable cardiovascular disease, stable diabetes mellitus, no significant nervous system disease).
  • Subject must have adequate vision, hearing and language abilities to complete assessments.

You may not qualify if:

  • Self-reported or clinically diagnosed late-stage dementia
  • Significant disease of the central nervous system
  • Severely depressed (CES-D score \> 16), significantly symptomatic psychiatric disorder
  • Advanced cardiovascular disease that would make walking difficult, including history of congestive heart failure
  • Unstable insulin-dependent diabetes mellitus, received diagnosis Type 1 Diabetes, started insulin within past 3 months, hospitalized for hypoglycemia within past 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oregon Health & Science University

Portland, Oregon, 97239, United States

Location

Related Publications (2)

  • Croff RL, Witter Iv P, Walker ML, Francois E, Quinn C, Riley TC, Sharma NF, Kaye JA. Things Are Changing so Fast: Integrative Technology for Preserving Cognitive Health and Community History. Gerontologist. 2019 Jan 9;59(1):147-157. doi: 10.1093/geront/gny069.

    PMID: 29961887BACKGROUND
  • Paula Carder, Raina Croff, Aliza Tuttle & Juell Towns (2022) Walking and Talking: Recommendations for Doing Mobile Interviews with Older Adults, Journal of Aging and Environment, DOI: 10.1080/26892618.2022.2030844

    BACKGROUND

Related Links

MeSH Terms

Conditions

Caregiver BurdenDepressionCognitive DysfunctionMotor Activity

Condition Hierarchy (Ancestors)

Stress, PsychologicalBehavioral SymptomsBehaviorCognition DisordersNeurocognitive DisordersMental Disorders

Study Officials

  • Raina L Croff, PhD

    OregonOHSU

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Triads are randomized into either the intervention group or the waitlist control group. The intervention group walks for 16 weeks. The waitlist control group completes baseline measures for 16 weeks then continues measures while walking 16 weeks. Wearable technology and weekly surveys are optional for PLWD.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Neurology

Study Record Dates

First Submitted

November 11, 2022

First Posted

December 20, 2022

Study Start

March 1, 2023

Primary Completion

October 20, 2024

Study Completion

October 20, 2024

Last Updated

October 24, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Locations