Postural Control Instability in Children With Mild Autism

NCT05644366 | Completed

• 1 other identifier: A2540214
• Study Type: interventional
• Target: 10
• Locations: 0 countries
• Sites: N/A

Brief Summary

Objective: Individuals diagnosed with Autism Spectrum Disorder (ASD) exhibit some type of motor control impairment, for instance, motor apraxia and history of gross motor delay that could lead to increased risk of fall. This pilot research was designed to assess and characterize static postural stability and create a starting point to better understand and describe postural control in children with mild autism. Method: We measured static postural control with center of pressure (COP) displacement in 10 children with mild autism during eight sensory conditions that challenge and cancel the visual, proprioceptive and vestibular systems.

Conditions

Autism Spectrum Disorder

Outcome Measures

Primary Outcomes (1)

• Postural Stability

  Postural stability was operationally defined by the center of pressure displacement measured by the MatScan® pressure mat. These sensors detect the displacement as the body sways anterior, posterior or laterally (right or left).

  Baseline

Study Arms (1)

Balance Assessment Children with Autism

EXPERIMENTAL

Postural Stability Testing Each subject was instructed to stand in a static bipedal posture on the MatScan® pressure mat and performed 8 balance tasks.

Other: Postural Control Balance Assessment

Interventions

Postural Control Balance Assessment OTHER

Postural Stability Testing Each subject was instructed to stand in a static bipedal posture on the MatScan® pressure mat and performed 8 balance tasks.

Balance Assessment Children with Autism

Eligibility Criteria

• Age: 7 Years - 12 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• children from 7-12 years of age, male or female
• mild ASD diagnosis (as determined by a medical doctor)
• capable of ambulating independently.

You may not qualify if:

• children with additional neurological problems
• children with visual problems
• children unable to tolerate walking or standing barefoot
• children who have fallen three or more times in the last three months
• children with vestibular problems.

Sponsors & Collaborators

• Texas Woman's University: lead

Related Publications (15)

• Ming X, Brimacombe M, Wagner GC. Prevalence of motor impairment in autism spectrum disorders. Brain Dev. 2007 Oct;29(9):565-70. doi: 10.1016/j.braindev.2007.03.002. Epub 2007 Apr 30.

  PMID: 17467940 BACKGROUND

• Teitelbaum P, Teitelbaum O, Nye J, Fryman J, Maurer RG. Movement analysis in infancy may be useful for early diagnosis of autism. Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13982-7. doi: 10.1073/pnas.95.23.13982.

  PMID: 9811912 BACKGROUND

• Fournier KA, Kimberg CI, Radonovich KJ, Tillman MD, Chow JW, Lewis MH, Bodfish JW, Hass CJ. Decreased static and dynamic postural control in children with autism spectrum disorders. Gait Posture. 2010 May;32(1):6-9. doi: 10.1016/j.gaitpost.2010.02.007. Epub 2010 Apr 18.

  PMID: 20400311 BACKGROUND

• Mari M, Castiello U, Marks D, Marraffa C, Prior M. The reach-to-grasp movement in children with autism spectrum disorder. Philos Trans R Soc Lond B Biol Sci. 2003 Feb 28;358(1430):393-403. doi: 10.1098/rstb.2002.1205.

  PMID: 12639336 BACKGROUND

• Kohen-Raz R, Volkmar FR, Cohen DJ. Postural control in children with autism. J Autism Dev Disord. 1992 Sep;22(3):419-32. doi: 10.1007/BF01048244.

  PMID: 1383190 BACKGROUND

• Fournier KA, Hass CJ, Naik SK, Lodha N, Cauraugh JH. Motor coordination in autism spectrum disorders: a synthesis and meta-analysis. J Autism Dev Disord. 2010 Oct;40(10):1227-40. doi: 10.1007/s10803-010-0981-3.

  PMID: 20195737 BACKGROUND

• Blanche EI, Reinoso G, Chang MC, Bodison S. Proprioceptive processing difficulties among children with autism spectrum disorders and developmental disabilities. Am J Occup Ther. 2012 Sep-Oct;66(5):621-4. doi: 10.5014/ajot.2012.004234.

  PMID: 22917129 BACKGROUND

• Shumway-Cook, A., & Woollacott, M. H. (2001a). Constraints of motor control. Motor control: Theory and practical applications (2nd ed., pp. 127-161). Philadelphia, Pa. ; London: Lippincott Williams & Wilkins.

  BACKGROUND

• Kern, J. K., Garver, C. R., Grannemann, B. D., Trivedi, M. H., Carmody, T., Andrews, A. A., & Mehta, J. A. (2007). Response to vestibular sensory events in autism. Research in Autism Spectrum Disorders, 1(1), 67-74. doi:10.1016/j.rasd.2006.07.006

  BACKGROUND

• Molloy CA, Dietrich KN, Bhattacharya A. Postural stability in children with autism spectrum disorder. J Autism Dev Disord. 2003 Dec;33(6):643-52. doi: 10.1023/b:jadd.0000006001.00667.4c.

  PMID: 14714933 BACKGROUND

• Shumway-Cook, A., & Woollacott, M. H. (2001b). Development of postural control. Motor control: Theory and practical applications (2nd ed., pp. 192-221). Philadelphia, Pa. ; London: Lippincott Williams & Wilkins.

  BACKGROUND

• FUKUDA T. The stepping test: two phases of the labyrinthine reflex. Acta Otolaryngol. 1959 Mar-Apr;50(2):95-108. doi: 10.3109/00016485909129172. No abstract available.

  PMID: 13636842 BACKGROUND

• Zammit GV, Menz HB, Munteanu SE. Reliability of the TekScan MatScan(R) system for the measurement of plantar forces and pressures during barefoot level walking in healthy adults. J Foot Ankle Res. 2010 Jun 18;3:11. doi: 10.1186/1757-1146-3-11.

  PMID: 20565812 BACKGROUND

• Hansson EE, Beckman A, Hakansson A. Effect of vision, proprioception, and the position of the vestibular organ on postural sway. Acta Otolaryngol. 2010 Dec;130(12):1358-63. doi: 10.3109/00016489.2010.498024. Epub 2010 Jul 16.

  PMID: 20632903 BACKGROUND

• O'sullivan, S. B. (2007). Examination of motor function: Motor control and motor learning. Physical rehabilitation (pp. 233-234) FA Davis Company Philadelphia.

  BACKGROUND

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Officials

• Martin G. Rosario, PT, PhD

  Texas Woman's University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: The balance assessment procedure included the following; each subject was instructed to stand on both feet for 15 seconds on the pressure MatScan under eight different conditions.

Study Record Dates

• First Submitted: February 28, 2018
• First Posted: December 9, 2022
• Study Start: August 14, 2014
• Primary Completion: August 14, 2015
• Study Completion: September 14, 2015
• Last Updated: December 9, 2022

Record last verified: 2022-12