NCT05638373

Brief Summary

The aim of the current study is to assess the shade matching potential of single shade universal resin composite versus conventional nanohybrid resin composite in class IV restorations after bleaching

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
32

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2023

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 27, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 6, 2022

Completed
9 months until next milestone

Study Start

First participant enrolled

September 12, 2023

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2025

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2025

Completed
Last Updated

August 6, 2024

Status Verified

August 1, 2024

Enrollment Period

1.4 years

First QC Date

November 27, 2022

Last Update Submit

August 4, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in shade matching

    Modified USPHS criteria with Alpha, Bravo ,Charlie and Delta scores (Categorical)

    Baseline, 2 days, 3, 6 and 12 months

Secondary Outcomes (2)

  • Change in Marginal discoloration

    Baseline, 2 days, 3, 6 and 12 months

  • Change in surface texture

    Baseline, 2 days, 3, 6 and 12 months

Study Arms (2)

One shade universal composite

EXPERIMENTAL

shade matching composite

Other: One shade universal composite

Nanohybrid resin composite

ACTIVE COMPARATOR

Conventional Nanohybrid resin composite

Other: Nanohybrid resin composite

Interventions

A resin composite with new smart chromatic technology and chameleon effect. It has the ability to match the new lighter shade of the bleached teeth unlike the conventional composite

One shade universal composite

A conventional resin composite with multiple shades

Nanohybrid resin composite

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Candidates must have one or more existing class IV restoration.
  • Cases indicated for bleaching.
  • Cooperative patient approving to participate in the trial.

You may not qualify if:

  • Patients with severe medical conditions that might interfere with the study.
  • Patients with rampant caries or xerostomia.
  • Smoking.
  • Patients with history of hydrogen peroxide sensitivity , periodontal inflammation.
  • Lack of compliance.
  • Tempromandibular joint disorders.
  • Disabilities.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry, cairo university

Cairo, 12613, Egypt

RECRUITING

Related Publications (8)

  • Ameedee AAL, Ragab H, Essam E, et al.(2016): Clinical evaluation of in-office tooth bleaching effects on three contemporary composite resins. J Dent Health Oral Disord Ther., 5(6):350-357.

    BACKGROUND
  • Bayne SC, Schmalz G. Reprinting the classic article on USPHS evaluation methods for measuring the clinical research performance of restorative materials. Clin Oral Investig. 2005 Dec;9(4):209-14. doi: 10.1007/s00784-005-0017-0. No abstract available.

    PMID: 16421996BACKGROUND
  • Elzayat, G. A., Elsayed, M. E., & El Zoghby, A. (2020): Clinical Performance of Direct Anterior Composite Restorations Using Esthetic Dual-Shade versus Polychromatic Natural Layering Technique: a split mouth randomized controlled clinical trial. Brazilian Dental Science, 23(4), 12-12.

    BACKGROUND
  • Evans, M. B. (2020):The Visual and Spectrophotometric Effect of External Bleaching on OMNICHROMA Resin Composite and Natural Teeth. West Virginia University.

    BACKGROUND
  • Mohamed, M. A., Afutu, R., Tran, D., Dunn, K., Ghanem, J., Perry, R., & Kugel, G. (2020): Shade Matching Capacity of Omnichroma in Anterior Restorations. Journal of Dental Sciences., 5(1), 1-6.

    BACKGROUND
  • Mourouzis P, Koulaouzidou EA, Helvatjoglu-Antoniades M. Effect of in-office bleaching agents on physical properties of dental composite resins. Quintessence Int. 2013 Apr;44(4):295-302. doi: 10.3290/j.qi.a29154.

    PMID: 23479582BACKGROUND
  • Pereira Sanchez N, Powers JM, Paravina RD. Instrumental and visual evaluation of the color adjustment potential of resin composites. J Esthet Restor Dent. 2019 Sep;31(5):465-470. doi: 10.1111/jerd.12488. Epub 2019 May 16.

    PMID: 31095870BACKGROUND
  • Telang A, Narayana IH, Madhu KS, Kalasaiah D, Ramesh P, Nagaraja S. Effect of Staining and Bleaching on Color stability and Surface Roughness of Three Resin Composites: An in vitro study. Contemp Clin Dent. 2018 Jul-Sep;9(3):452-456. doi: 10.4103/ccd.ccd_297_18.

    PMID: 30166843BACKGROUND

Study Officials

  • ahmed El Zoheiry, prof

    Cairo University

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Master degree candidate, Department of Conservative Dentistry, Faculty of Dentistry

Study Record Dates

First Submitted

November 27, 2022

First Posted

December 6, 2022

Study Start

September 12, 2023

Primary Completion

February 1, 2025

Study Completion

October 1, 2025

Last Updated

August 6, 2024

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will not share

Locations