NCT05629936

Brief Summary

In this study, a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas will be developed and evaluated. The primary objective is to evaluate the effect of the service regarding the identification, classification, and resolution of medication-related problems (MRPs). Secondary objectives are to evaluate participants' medication adherence, health-related quality of life, and beliefs about medicines through self-report questionnaires. The telepharmacy service include medication interviews, structured medication reviews, interdisciplinary patient-centred discussions, and follow-ups.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
28mo left

Started Nov 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress54%
Nov 2023Dec 2028

First Submitted

Initial submission to the registry

November 7, 2022

Completed
22 days until next milestone

First Posted

Study publicly available on registry

November 29, 2022

Completed
12 months until next milestone

Study Start

First participant enrolled

November 22, 2023

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2027

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2028

Last Updated

May 5, 2026

Status Verified

April 1, 2026

Enrollment Period

4 years

First QC Date

November 7, 2022

Last Update Submit

April 28, 2026

Conditions

Keywords

TelemedicineMedication reconciliationClinical pharmacistAdherenceTelepharmacyMedication-related problemsAgedStructured medication review

Outcome Measures

Primary Outcomes (5)

  • Identification and classfication of medication-related problems

    Classification of mediation-related problems according to a modified version of the classification system by Cipolle et al (1998).

    The 12-week intervention period

  • Resolution of medication-related problems

    The clinical pharmacists' recommendations to resolve medication-related problems will be classified according to a modified version of a system developed by the French Society of Clinical pharmacy. Physicians' acceptance rate of pharmacists' recommendations will be classified. The acceptance rate will be classified as accepted recommendation, rejected recommendation, or unknown.

    12-week intervention period

  • Intra-individual change in self-reported medication adherence: Medication Adherence Report Scale-5 (MARS-5)

    Assessing self-reported medication adherence through the MARS-5 questionnaire. Total score ranging between 5 and 25, with higher scores indicating a higher level of medication adherence.

    Baseline and 12 weeks

  • Intra-individual change in self-reported health-related quality of life: EuroQol-5 Dimension-5 Level questionnaire (EQ-5D-5L)

    Assessing health-related quality of life through the EQ-5D-5L-questionnaire. The questionnaire consists of five questions regarding self-perceived quality of life, and a visual analogue scale on which the respondents evaluate their own health status on a scale of 0-100.

    Baseline and 12 weeks

  • Intra-individual change in self-reported beliefs about medicines: The Beliefs about Medicines Questionnaire (BMQ)

    Assessing beliefs about medicines through the BMQ. The questionnaire consists of two different scales; BMQ-General assesses the respondent's beliefs about medicines in general and BMQ-Specific evaluates the individual's beliefs about medicines prescribed for their own use.

    Baseline and 12 weeks

Study Arms (1)

Digital intervention

OTHER

Video-based telepharmacy service

Other: Telepharmacy service

Interventions

Video-based medication interviews, structured medication reviews, interdisciplinary patient-centred discussions, follow-ups

Digital intervention

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Using five or more prescribed medications and/or considered as a potential candidate by the primary care physician.
  • Living at home (i.e not in a nursing home)
  • Registered at primary healthcare centres in rural municipalities within Västerbotten County (and neighbouring counties if necessary)

You may not qualify if:

  • Do not speak Swedish
  • Unable to communicate
  • Has a confirmed major neurocognitive disorder
  • Receives palliative care

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Åsele healthcare centre

Åsele, Sweden

Location

Storuman healthcare centre

Storuman, Sweden

Location

Related Publications (1)

  • Westberg A, Andersson P, Sonnerstam E, Mattsson S, Holmner A, Edin-Liljegren A, Gustafsson M. Development and evaluation of a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas: protocol for a single-arm interventional study. BMJ Open. 2025 Nov 19;15(11):e110198. doi: 10.1136/bmjopen-2025-110198.

Study Officials

  • Maria Gustafsson, Ph.D

    Department of Medical and Translational Biology, Umeå University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

November 7, 2022

First Posted

November 29, 2022

Study Start

November 22, 2023

Primary Completion (Estimated)

December 1, 2027

Study Completion (Estimated)

December 1, 2028

Last Updated

May 5, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Individual participant data (IPD) will not be shared or publicly available due to privacy and ethical restrictions.

Locations