10-year Follow-up After Tibial Tubercle Transposition

NCT05629754 | Unknown DMC

• 1 other identifier: NL82613.029.22
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

Patellofemoral pain is a common complaint especially in young adults. It can be caused by patellar maltracking. Part of this is a patella alta. When patellar maltracking is the cause of the problem and conservative therapy fails, surgery, a tibial tuberosity transposition, may be considered. Most research has been done in patients with recurrent patella luxation. However, in patients without luxation, research is scarce. It is known that patients with patella alta have an increased risk of developing patellofemoral chondropathy due to increased pressure. With this study, we aim to investigate whether and how a tibial tuberosity transposition in patients with patella alta and no instability affects the degree of patellofemoral chondropathy and patient satisfaction after 10 years. This will allow us to educate patients regarding long-term outcomes better.

Conditions

Anterior Knee Pain Syndrome

Keywords

Tibial tubercle transfer; Long-term follow-up

Outcome Measures

Primary Outcomes (1)

• Modified Outerbridge Classification

  Degree of retropatellar cartilage damage

  10-year follow-up assessment

Secondary Outcomes (4)

• Patellar height

  10-year follow-up assessment

• Knee injury and Osteoarthritis Outcome Score (KOOS) questionnaire

  10-year follow-up assessment

• Kujala Anterior Knee Pain Score (AKPS) questionnaire

  One measurement

• Visual Analogue Scale (VAS) for pain

  10-year follow-up assessment

Interventions

MRI, radiological assessment DIAGNOSTIC_TEST

MRI and radiological assessment of the involved knee

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients whom around 10 years ago presented with anterior knee pain and patella maltracking without instability, where conservative therapy failed and a TTT was performed, and who participated in the original cohort.

You may qualify if:

• Age between 18 and 80 years
• Participated in an earlier cohort study
• Underwent a tibial tubercle transposition between 2012 and 2015
• Preoperative MRI available

You may not qualify if:

• No preoperative MRI is available
• Patellar-related surgery after the initial surgery
• Female patients that are (expecting to be) pregnant

Sponsors & Collaborators

• Centre for Orthopaedic Research Alkmaar: lead
• Noordwest Ziekenhuisgroep: collaborator

Study Sites (1)

Noordwest Ziekenhuisgroep

Alkmaar, North Holland, 1815 JD, Netherlands

Location

Related Publications (1)

• Bayoumi T, van Duijvenbode DC, Benner JL, Boerma-Argelo KDS, Stavenuiter MHJ, van der List JP. Clinical Improvement Is Achieved Following Tibial Tubercle Distomedialization for Patellar Maltracking and Patella Alta Without Instability. Arthrosc Sports Med Rehabil. 2021 Jun 15;3(3):e845-e853. doi: 10.1016/j.asmr.2021.01.027. eCollection 2021 Jun.

  PMID: 34195653 BACKGROUND

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Interventions

Magnetic Resonance Imaging

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• JL Benner, PhD

  Noordwest Ziekenhuisgroep

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 9, 2022
• First Posted: November 29, 2022
• Study Start: November 18, 2023
• Primary Completion: December 1, 2024
• Study Completion: December 1, 2024
• Last Updated: November 24, 2023

Record last verified: 2023-11

Locations

NL (1)