Cognitive Remote Assessment Using FLAME (CRA-FLAME)

NCT05624632 | Enrolling By Invitation

• 1 other identifier: CRA- FLAME/BBRC2022
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

We aim to use a multimodal approach comprising conventional neuropsychological cognitive tests, fluid and imaging biomarker data, to explore their association with the FLAME unsupervised cognitive computerized assessment. We believe that this would provide critical information to move forward the current research framework in the field. Participants will be selected from BBRC-sponsored studies, such as the ALFA project (STUDY 45-65 FPM/2012), the ALFA+ cohort study (ALFA - FPM - 0311), the Beta-AARC study (β-AARC\_BBRC2020) or the BarcelonaBeta Dementia Prevention Research Clinic study (BBRC-DemPrev-2018)

Conditions

Cognitive Impairment

Outcome Measures

Primary Outcomes (1)

• FLAME global composite score

  calculated by combining information from two web-based online neuropsychological test batteries that are already integrated in a unique platform: the PROTECT Cognitive Tests System (PCTS) (Corbett et al., 2015) and the CogTrackTM (Wesnes et al., 2017)

  through study completion, an average of 3 years

Study Arms (1)

Cognitively unimpaired

Cognitively unimpaired participants from BBRC-sponsored studies

Other: Remote cognitive testing

Interventions

Remote cognitive testing OTHER

Remote cognitive testing

Cognitively unimpaired

Eligibility Criteria

• Age: 45 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants are individuals that have participated/are participating in BBRC-sponsored studies.

You may qualify if:

• Participants must meet ALL the following criteria:
• To sign the study informed consent form approved by the corresponding authorities.
• Men and women that have participated/are participating in a BBRC-sponsored study.
• To accept that:
• The results obtained in this study may be published in scientific journals and at BBRC's communication channels (e.g. web page)
• The data gathered may be used in combination with those gathered in other BBRC-sponsored studies in which they may (have) participate(d)

You may not qualify if:

• \. Not having an ICT literacy enough to access and complete the online tests.

Sponsors & Collaborators

• Barcelonabeta Brain Research Center, Pasqual Maragall Foundation: lead

Study Sites (1)

BarcelonaBeta Brain Research Center

Barcelona, 08005, Spain

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 8, 2022
• First Posted: November 22, 2022
• Study Start: December 1, 2022
• Primary Completion: December 1, 2025
• Study Completion (Estimated): December 1, 2026
• Last Updated: May 31, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)