Telerehabilitation Based Exercise Training in Parkinson's Patients

NCT05621642 | Unknown DMC

• 1 other identifier: IstanbulUC-MAZI-001
• Study Type: interventional
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

Parkinson's disease (PD) is the second most common progressive disease after Alzheimer's disease.It is a progressive, multisystemic and neurodegenerative disease. The prevalence of Parkinson's disease increases with age. increases together. In industrialized countries, people over the age of 60 account for 0.3% of the entire population.It affects about 1% of people and 3% of people over the age of 80 .Patient management with telerehabilitation (TR), chronic heart disease, neurological dysfunction.It is as effective as face-to-face treatment in different clinical conditions such as musculoskeletal and musculoskeletal disorders proven . In addition, TR will increase accessibility and create a less restrictive environment. comparable to traditional rehabilitation as it provides new opportunities to create not only can it be more effective than it . Intense exercise and long-term training In cases where it is necessary, it is accepted to continue exercise therapy with TR programs at home.may be a viable solution.When telerehabilitation-based studies are examined, communication, swallowing and walking are generally focused on parameters. Treatment with telerehabilitation method in PD, Studies investigating the effects on respiratory and postural instability parameters are quite is limited . The aim of this study is to improve telerehabilitation-based exercise training in PD. respiratory muscle strength, cough capacity, dynamic balance, participation in activities of daily living and to investigate its effect on walking parameters. also online physiotherapist.Comparing the effects of supervised exercises and offline video-based exercise training intended.

Conditions

Parkinson Disease; Respiration; Gait Disorders, Neurologic

Keywords

telerehabilitation; balance; parkinson

Outcome Measures

Primary Outcomes (3)

• Timed up and go test

  In the timed up and go test, subjects are asked to rise from a standard arm chair, walk to a marker 3 m away, turn, walk back, and sit down again. The test is a reliable and valid test for quantifying functional mobility that may also be useful in following clinical change over time.

  3 minute

• Respiratory Strength Assesment

  MIP and MEP value will be measured.

  3 minute

• Peak Cough Stream Assesment

  Changed motor control of cough as there is a change in force production using the expiratory muscles

  3 minute

Secondary Outcomes (4)

• Tinetti balance Test

  5 minute

• 10 m Walking Test

  3 minute

• Parkinson's Activity Scale Parkinson Activity Test

  5 minute

• Unified Parkinson's Disease Rating Scale

  5 minute

Study Arms (2)

Online Group

EXPERIMENTAL

Trainings will be given to the intervention group patients by the researchers. Respiratory, balance and strengthening exercises suitable for the patients will be applied over an online platform under the supervision of a physiotherapist.

Other: Breathing exercises; Other: Core stabilization exercises; Other: Balance and strengthening exercises

Offline Group

ACTIVE COMPARATOR

The exercises will be video recorded gradually every two weeks and the exercise program of each week will be sent to the patient. The patient will do respiratory, balance and strengthening exercises accompanied by video.

Other: Breathing exercises; Other: Core stabilization exercises; Other: Balance and strengthening exercises

Interventions

Breathing exercises OTHER

In the sitting position, the patient does 15 diaphragm breathing and 15 huffing exercises.

Offline Group; Online Group

Core stabilization exercises OTHER

This intervention includes bridging exercise and abdominal exercises.

Offline Group; Online Group

Balance and strengthening exercises OTHER

It includes sitting and standing on the chair 15 times and turning around the chair.

Offline Group; Online Group

Eligibility Criteria

• Age: 45 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having been diagnosed with PH by a neurologist,
• Being between 45 and 85 years old,
• Being between I and III according to the modified Hoehn \& Yahr Staging (29)
• To have a score of 24 or higher in the Mini Mental State Assessment (30),
• To be taking their medication regularly.

You may not qualify if:

• Having an orthopedic disability that will affect balance and mobility,
• Those with serious chronic diseases that will significantly affect their quality of life (congestive heart failure, myocardial infarction),
• Severe dyskinesia, cognitive problem that prevents cooperation,
• Not having internet access with a smart phone or computer,

Sponsors & Collaborators

• Istanbul University - Cerrahpasa: lead

Related Publications (13)

• Lee A, Gilbert RM. Epidemiology of Parkinson Disease. Neurol Clin. 2016 Nov;34(4):955-965. doi: 10.1016/j.ncl.2016.06.012. Epub 2016 Aug 18.

  PMID: 27720003 BACKGROUND

• Peretti A, Amenta F, Tayebati SK, Nittari G, Mahdi SS. Telerehabilitation: Review of the State-of-the-Art and Areas of Application. JMIR Rehabil Assist Technol. 2017 Jul 21;4(2):e7. doi: 10.2196/rehab.7511.

  PMID: 28733271 BACKGROUND

• McCue M, Fairman A, Pramuka M. Enhancing quality of life through telerehabilitation. Phys Med Rehabil Clin N Am. 2010 Feb;21(1):195-205. doi: 10.1016/j.pmr.2009.07.005.

  PMID: 19951786 BACKGROUND

• Silverman EP, Sapienza CM, Saleem A, Carmichael C, Davenport PW, Hoffman-Ruddy B, Okun MS. Tutorial on maximum inspiratory and expiratory mouth pressures in individuals with idiopathic Parkinson disease (IPD) and the preliminary results of an expiratory muscle strength training program. NeuroRehabilitation. 2006;21(1):71-9.

  PMID: 16720940 BACKGROUND

• Saleem AF, Sapienza CM, Okun MS. Respiratory muscle strength training: treatment and response duration in a patient with early idiopathic Parkinson's disease. NeuroRehabilitation. 2005;20(4):323-33.

  PMID: 16403998 BACKGROUND

• Wirdefeldt K, Adami HO, Cole P, Trichopoulos D, Mandel J. Epidemiology and etiology of Parkinson's disease: a review of the evidence. Eur J Epidemiol. 2011 Jun;26 Suppl 1:S1-58. doi: 10.1007/s10654-011-9581-6. Epub 2011 May 28.

  PMID: 21626386 BACKGROUND

• Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. Am J Epidemiol. 2003 Jun 1;157(11):1015-22. doi: 10.1093/aje/kwg068.

  PMID: 12777365 BACKGROUND

• Lotankar S, Prabhavalkar KS, Bhatt LK. Biomarkers for Parkinson's Disease: Recent Advancement. Neurosci Bull. 2017 Oct;33(5):585-597. doi: 10.1007/s12264-017-0183-5. Epub 2017 Sep 21.

  PMID: 28936761 BACKGROUND

• Kim Y, Lai B, Mehta T, Thirumalai M, Padalabalanarayanan S, Rimmer JH, Motl RW. Exercise Training Guidelines for Multiple Sclerosis, Stroke, and Parkinson Disease: Rapid Review and Synthesis. Am J Phys Med Rehabil. 2019 Jul;98(7):613-621. doi: 10.1097/PHM.0000000000001174.

  PMID: 30844920 BACKGROUND

• Cheng DK, Nelson M, Brooks D, Salbach NM. Validation of stroke-specific protocols for the 10-meter walk test and 6-minute walk test conducted using 15-meter and 30-meter walkways. Top Stroke Rehabil. 2020 May;27(4):251-261. doi: 10.1080/10749357.2019.1691815. Epub 2019 Nov 21.

  PMID: 31752634 BACKGROUND

• Nieuwboer A, De Weerdt W, Dom R, Bogaerts K, Nuyens G. Development of an activity scale for individuals with advanced Parkinson disease: reliability and "on-off" variability. Phys Ther. 2000 Nov;80(11):1087-96.

  PMID: 11046196 BACKGROUND

• Feng H, Li C, Liu J, Wang L, Ma J, Li G, Gan L, Shang X, Wu Z. Virtual Reality Rehabilitation Versus Conventional Physical Therapy for Improving Balance and Gait in Parkinson's Disease Patients: A Randomized Controlled Trial. Med Sci Monit. 2019 Jun 5;25:4186-4192. doi: 10.12659/MSM.916455.

  PMID: 31165721 BACKGROUND

• Soke F, Guclu-Gunduz A, Kocer B, Fidan I, Keskinoglu P. Task-oriented circuit training combined with aerobic training improves motor performance and balance in people with Parkinson's Disease. Acta Neurol Belg. 2021 Apr;121(2):535-543. doi: 10.1007/s13760-019-01247-8. Epub 2019 Nov 18.

  PMID: 31741209 BACKGROUND

MeSH Terms

Conditions

Parkinson Disease; Respiratory Aspiration; Gait Disorders, Neurologic

Interventions

Breathing Exercises

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Tuğba Argün Pulat

  Doctor in hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rüstem Mustafaoğlu

CONTACT

05554178535; rustem.mustafaoglu@iuc.edu.tr

İlknur Mazı

CONTACT

05417319232; mazilknur@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 28, 2022
• First Posted: November 18, 2022
• Study Start: November 20, 2022
• Primary Completion: March 13, 2023
• Study Completion: June 5, 2023
• Last Updated: November 18, 2022

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share