Low Psoas Index and Cardiac Assistance: No Excess Mortality at D28 Post Implantation

NCT05612555 | Completed

• 1 other identifier: 7531
• Study Type: observational
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

The frailty syndrome is important to consider in perioperative cardiac assistance. One of its components is the patient's sarcopenia. This can be assessed by measuring the size of the psoas muscle. For this purpose, one of the most studied measures seems to be the measurement of the Psoas Index. This is a contouring of the psoas muscle, performed on an axial section of a CT scan, at the level of the L4 vertebra, which is then matched to the body surface. However, there is no standardization of measurements and volume acquisitions, and different image processing is also described. A radiological evaluation of the psoas could overcome this difficulty and provide a rapid and available screening tool for sarcopenia.

Conditions

Ventricular Assist Device

Keywords

Ventricular Assist Device; VAD; Sarcopenia; Psoas Index; Cardiac assistance; Cardiac assistance surgery

Outcome Measures

Primary Outcomes (1)

• Impact of sarcopenia, measured by the Psoas Index, on 28-day survival in patients undergoing cardiac assistance surgery

  Survival at 28 days after surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Major subject ((≥18 years old) having surgery for placement of a ventricular assist device between 01/02/2014 and 30/06/2018 in Strasbourg University Hospital

You may qualify if:

• Major subject ((≥18 years old)
• Subject who underwent surgery for placement of a ventricular assist device between 01/02/2014 and 30/06/2018
• Subject who has not expressed opposition to the reuse of his or her data for research purposes

You may not qualify if:

• Subject having expressed opposition to participate in the study
• Absence of CT scan available at the time of implantation or CT scans older than one year prior to surgery and those older than 72 hours postoperatively
• No anthropometric data available
• Subject under legal protection
• Subject under guardianship or curatorship

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service de Réanimation Chirurgicale - CHU de Strasbourg - France

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 3, 2022
• First Posted: November 10, 2022
• Study Start: September 9, 2019
• Primary Completion: July 9, 2020
• Study Completion: September 9, 2020
• Last Updated: December 14, 2023

Record last verified: 2023-12

Locations

FR (1)