Experience and Feasibility of Methods for Early Sensory Training

NCT05611983 | Recruiting

• 1 other identifier: Dnr 2021-03519
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The good effects of using guided plasticity for a rehabilitative purpose in case of nerve damage have been shown, but a problem that has been presented is that some individuals find it difficult to assimilate these effects due to difficulties in carrying out abstract training or due to a lack of motivation. In early sensory training, the plasticity of the brain is used. Methods for early sensory training that have been described are: 1) mental imagery of touch (mental imagery), 2) observation of touch, 3) mirror training, 4) use of images for visualization of touch. The method needs to be developed and refined to be able to offer individual training plans in order to find a motivating and meaningful form of training.

Conditions

Nerve Injury; Peripheral Nerve Injuries

Keywords

periferal nerve injuries; sensory relearning; rehabilitation; imagery; mirror therapy

Outcome Measures

Primary Outcomes (2)

• PETS - The Problematic Experience of Therapy Scale

  questionnaire, 5-grading scale from "strongly agree" to 'strongly disagree'' to all items in a subscale are recoded as ''no barriers'', and all other scores are recoded as ''some barriers or doubts'' for completing the therapy/sensory relearning.

  4 weeks post intervention

• ESRQ - Early sensory relearing questionaire

  questionnaire, 5-grading scale from "strongly agree" to 'strongly disagree''

  4 weeks post intervention

Study Arms (4)

Observation fo touch

ACTIVE COMPARATOR

Behavioral: sensory relearning

Observation of pictures

ACTIVE COMPARATOR

Behavioral: sensory relearning

Imagery of touch

ACTIVE COMPARATOR

Behavioral: sensory relearning

Mirror therapy

ACTIVE COMPARATOR

Behavioral: sensory relearning

Interventions

sensory relearning BEHAVIORAL

feasibility of early sensory relearning

Imagery of touch; Mirror therapy; Observation fo touch; Observation of pictures

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \>= 50% injury of N. Medianus/ N. Ulnaris or 100% digital nerve injury dig I and/or dig II
• Ålder: ≥ 18 år

You may not qualify if:

• Impaired cognitive ability
• Documented psychiatric diagnosis
• Inability to master the Swedish language

Sponsors & Collaborators

• Lund University Hospital: lead

Study Sites (1)

Skane university hospital

Malmo, Skåne County, 20502, Sweden

RECRUITING

Related Publications (5)

• Vikstrom P, Carlsson I, Rosen B, Bjorkman A. Patients' views on early sensory relearning following nerve repair-a Q-methodology study. J Hand Ther. 2018 Oct-Dec;31(4):443-450. doi: 10.1016/j.jht.2017.07.003. Epub 2017 Sep 28.

  PMID: 28967458 BACKGROUND

• Rosen B, Vikstrom P, Turner S, McGrouther DA, Selles RW, Schreuders TA, Bjorkman A. Enhanced early sensory outcome after nerve repair as a result of immediate post-operative re-learning: a randomized controlled trial. J Hand Surg Eur Vol. 2015 Jul;40(6):598-606. doi: 10.1177/1753193414553163. Epub 2014 Oct 7.

  PMID: 25294735 BACKGROUND

• Bassolino M, Campanella M, Bove M, Pozzo T, Fadiga L. Training the motor cortex by observing the actions of others during immobilization. Cereb Cortex. 2014 Dec;24(12):3268-76. doi: 10.1093/cercor/bht190. Epub 2013 Jul 29.

  PMID: 23897648 BACKGROUND

• Duffau H. Brain plasticity: from pathophysiological mechanisms to therapeutic applications. J Clin Neurosci. 2006 Nov;13(9):885-97. doi: 10.1016/j.jocn.2005.11.045. Epub 2006 Oct 17.

  PMID: 17049865 BACKGROUND

• Vikstrom P, Rosen B, Carlsson IK, Bjorkman A. The effect of early relearning on sensory recovery 4 to 9 years after nerve repair: a report of a randomized controlled study. J Hand Surg Eur Vol. 2018 Jul;43(6):626-630. doi: 10.1177/1753193418767024. Epub 2018 Apr 16.

  PMID: 29661095 RESULT

MeSH Terms

Conditions

Peripheral Nerve Injuries

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Officials

• Lars Dahlin, Prof

  Lund University/Region Skane

  STUDY CHAIR

Central Study Contacts

Ulrika Wijk, PhD

CONTACT

+4640331744; ulrika.wijk@med.lu.se

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: The outcome assessor/investigator are blinded from which intervention given.
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 3, 2022
• First Posted: November 10, 2022
• Study Start: June 1, 2022
• Primary Completion: June 1, 2024
• Study Completion: June 1, 2024
• Last Updated: March 15, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share

Locations

SE (1)