Impact of Health Lifestyle on Body Weight

NCT05608226 | Completed DMC

• 1 other identifier: ZSE-2210
• Study Type: observational
• Target: 128
• Locations: 1 country
• Sites: 1

Brief Summary

Pharmacotherapy becomes an important and effective approach to improve body weight. However, it still remains unclear how to manage potential fluctuation after its cessation. Lifestyle change is the foundation and included as a part of clinical routine in real-world, therefore, we plan to conduct a prospective study to assess the impact of health lifestyle education and related lifestyle adherence on body weight in Chinese people who live with obesity or overweight and are off-pharmacotherapy trial. The aim of this study is to examine the impact of lifestyle education and related lifestyle adherence on body weight related parameters in 6 months from treatment. In addition, body weight related results will be described.

Conditions

Body-Weight Trajectory

Outcome Measures

Primary Outcomes (1)

• Change in body weight

  To examine the change in body weight from baseline to 6 months following lifestyle education.

  6 months

Secondary Outcomes (3)

• Change in blood lipids

  6 months

• Change in glycemic control

  6 months

• Change in blood pressure

  6 months

Study Arms (2)

Lifestyle Education Group

Participants chose to receive a structured remotely delivered lifestyle education program during the 26-week weight loss maintenance period.

Behavioral: Lifestyle Education Program

Non-Education Group

Participants chose not to receive the structured lifestyle education program during the 26-week weight loss maintenance period.

Interventions

Lifestyle Education Program BEHAVIORAL

A remotely delivered structured lifestyle education program adapted from conventional lifestyle interventions

Lifestyle Education Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%) and consented to this study.

You may qualify if:

• All patients who completed a pharmacotherapy trial with clinically meaningful weight loss (≥5%)
• Those who consent to this study

You may not qualify if:

• Those who do not consent to this study

Sponsors & Collaborators

• Shanghai Zhongshan Hospital: lead

Study Sites (1)

Xiaoying Li

Shanghai, China

Location

MeSH Terms

Conditions

Body-Weight Trajectory

Condition Hierarchy (Ancestors)

Body Weight Changes; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 2, 2022
• First Posted: November 8, 2022
• Study Start: September 15, 2022
• Primary Completion: July 7, 2023
• Study Completion: July 7, 2023
• Last Updated: July 10, 2026

Record last verified: 2022-11

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)