NCT05607836

Brief Summary

a randomized, parallel, non-blinded trial in a single Emergency Mdeical Service in Poland within a group of 34 ground ambulances crews, comparing time and first pass success (FPS) for endotracheal intubation (ETI) in DL using the IntuBrite® (INT) and Macintosh laryngoscope (MCL) during cardiopulmonary resuscitation (CPR). intubations will be performed using INT and MCL based on an intention-to-treat analysis. The FPS time of the ETI attempt will be analysed. First attempt success will be counted.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
86

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2016

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2020

Completed
2.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2022

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

October 28, 2022

Completed
10 days until next milestone

First Posted

Study publicly available on registry

November 7, 2022

Completed
Last Updated

November 7, 2022

Status Verified

November 1, 2022

Enrollment Period

4 years

First QC Date

October 28, 2022

Last Update Submit

November 2, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Intubation time

    Endotracheal intubation from grabbing device to placement of tube in the trachea confirmed by EtCO2

    1 minute

Secondary Outcomes (2)

  • Intubation success

    1 minute

  • intubation complications

    5 minutes

Study Arms (2)

Intu-Brite

EXPERIMENTAL

Use of new laryngoscope - IntuBrite for intubation

Device: IntuBrite intubation

Macintosh

ACTIVE COMPARATOR

Use of standard laryngoscope with Macintosh blade for intubation

Device: Macintosh laryngoscope

Interventions

Use of new laryngoscope IntuBrite for intubation in patients with cardiopulmonary arrest and during resuscitation

Intu-Brite

Use of standard Macintosh blade laryngoscope for intubation in patients with cardiac arrest and requiring cardiopulmonary resuscitation

Macintosh

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients in cardiac arrest , requiring cardiopulmonary resuscitation

You may not qualify if:

  • suspected difficult intubation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University of Lodz, Poland

Lodz, 90-153, Poland

Location

Related Publications (1)

  • Kluj P, Fedorczak M, Gaszynski T, Ratajczyk P. A pilot, prospective trial of IntuBrite(R) versus Macintosh direct laryngoscopy for paramedic endotracheal intubation in out of hospital cardiac arrest. BMC Emerg Med. 2023 Jun 23;23(1):70. doi: 10.1186/s12873-023-00845-3.

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Tomasz Gaszynski

    Medical University of Lodz, Poland

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2022

First Posted

November 7, 2022

Study Start

January 1, 2016

Primary Completion

January 1, 2020

Study Completion

June 1, 2022

Last Updated

November 7, 2022

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share

Locations