NCT05602987

Brief Summary

To evaluate whether receiving enema before anal surgery or not affects the postoperative recovery and complications.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
282

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 29, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 2, 2022

Completed
12 days until next milestone

Study Start

First participant enrolled

November 14, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2023

Completed
Last Updated

November 22, 2023

Status Verified

November 1, 2023

Enrollment Period

10 months

First QC Date

October 29, 2022

Last Update Submit

November 20, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Pain score

    record max pain score(visual analog scale:0-10) each day

    On postoperative day 0 to day 7

  • Consumption of analgesics

    daily consumption of oral analgesics from post-operative day 0 to day 7

    On postoperative day 0 to day 7

Secondary Outcomes (3)

  • Incidence of surgical site infection

    On postoperative day 0-30

  • Incidence of Urinary retention

    On postoperative day 0 to day 7

  • First defecation after surgery

    On postoperative day 0 to day 7

Study Arms (2)

Study Group: enema

EXPERIMENTAL

receiving enema at the night before anal surgery

Procedure: enema

Control Group: no enema

ACTIVE COMPARATOR

no enema before anal surgery

Procedure: no enema

Interventions

enemaPROCEDURE

receiving enema at the night before anal surgery

Study Group: enema
no enemaPROCEDURE

no enema before anal surgery

Control Group: no enema

Eligibility Criteria

Age20 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who underwent hemorrhoidectomy, including circular stapled hemorrhoidopexy (PPH) and conventional hemorrhoidectomy
  • Patients who underwent fistulotomy or fistulectomy

You may not qualify if:

  • Emergency surgery
  • Surgery other than circular stapled hemorrhoidopexy (PPH) and conventional hemorrhoidectomy, e.g., rubber band ligation, injection treatment, and cryosurgery
  • Complicated fistulectomy, e.g., requiring surgical drainage and seton placement
  • Other types of anal surgery, e.g., anal fissure and colorectal cancer
  • Liver cirrhosis
  • Coagulation dysfunction
  • Bedridden
  • Human immunodeficiency virus infection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Taipei Medical University Shuang-Ho Hospital

New Taipei City, 235, Taiwan

Location

MeSH Terms

Conditions

HemorrhoidsFistula

Interventions

Enema

Condition Hierarchy (Ancestors)

Rectal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesVascular DiseasesCardiovascular DiseasesPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Drug TherapyTherapeutics

Study Officials

  • Tung Cheng Chang, MD, PHD

    Taipei Medical University Shuang Ho Hospital

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief of Colorectal Surgery

Study Record Dates

First Submitted

October 29, 2022

First Posted

November 2, 2022

Study Start

November 14, 2022

Primary Completion

September 10, 2023

Study Completion

October 31, 2023

Last Updated

November 22, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will share

The datasets used in this study can be obtained from the investigator upon reasonable request.

Shared Documents
STUDY PROTOCOL
Time Frame
data is available as the study is complete and for 12 month period
Access Criteria
will be shared upon request

Locations