Racial Differences in Yoga-Induced Responses

NCT05598073 | Withdrawn

• 1 other identifier: 6877
• Study Type: interventional
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to 1) determine whether racial differences are evident in resting arterial stiffness and ambulatory blood pressure between African Americans and Caucasians 2) compare heart rate, blood pressure and cytokine production responses to exercise (yoga) between African Americans and Caucasians; 3) compare isokinetic muscular strength between racial groups; and 4) determine if correlations exist between these measures.

Conditions

Cardiovascular and Immune Responses to Yoga

Outcome Measures

Primary Outcomes (6)

• Arterial stiffness

  Cardio-ankle vascular index

  Once at baseline

• Ambulatory blood pressure

  24 hours of ambulatory blood pressure monitoring

  Once at baseline

• Isokinetic strength

  Isokinetic leg extension and flexion strength assessments at 60,120,210,300, and 400 degrees per second

  Once at baseline

• Inflammatory markers

  Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

  Once at baseline

• Inflammatory markers

  Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

  Once 30 minutes into the 1-hour yoga session

• Inflammatory markers

  Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

  Once immediately after the 1-hour yoga session

Study Arms (1)

1-hour vinyasa yoga session

EXPERIMENTAL

Participants will complete a 1-hour vinyasa yoga DVD.

Behavioral: Vinyasa yoga session

Interventions

Vinyasa yoga session BEHAVIORAL

One hour of vinyasa yoga will be completed.

1-hour vinyasa yoga session

Eligibility Criteria

• Age: 18 Years - 39 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men between the ages of 18 and 39 (25 African American and 25 Caucasian) that are not professional or collegiate athletes
• Must exercise at least 3 days per week and have no more than 1 month of yoga practice.

You may not qualify if:

• Having stage 2 hypertension (\>130 mmHg for systolic / \>90 mmHg for diastolic) or higher or having taken BP medications within the 3 months prior to testing
• Infection within the previous 4 weeks
• Known renal disease
• Prior myocardial infarction
• Known coronary artery disease
• Personal history of stroke
• Heart failure
• Cardiac arrhythmias
• Chronic obstructive pulmonary disease
• Recent chest pain or dyspnea
• Orthopedic limitations that preclude the execution of yoga postures
• Current insulin dependence
• Chronic inflammatory conditions
• Blindness or deafness as participants will need to follow a yoga DVD in order to complete the session
• Having practiced yoga for more than 1 month

Sponsors & Collaborators

• Texas State University: lead

Study Sites (1)

Stacy Hunter

San Marcos, Texas, 78666, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 8, 2020
• First Posted: October 28, 2022
• Study Start: January 15, 2020
• Primary Completion: June 1, 2020
• Study Completion: July 1, 2020
• Last Updated: October 28, 2022

Record last verified: 2020-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)