Translation and Validation of the Intensive Care Unit Mobility Scale (IMS)

NCT05591950 | Completed

• 1 other identifier: TAVIMS
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Intensive care unit acquired weakness (ICUAW) is a common issue in critically ill patients. Early mobilization can reduce the occurrence of ICUAW. This requires a standardized procedure based on validated scales. One such scale is Carol Hodgson's ICU Mobility Scale (IMS). The subject of the study is the translation of the IMS into German and the validation of its reliability and predictive power with regard to various clinical outcomes. Furthermore we want to investigate the communication about the mobilisation status of ICU-patients between the different medical disciplines that are involved in patient care.

Conditions

Muscle Weakness; Critical Illness; Mechanical Ventilation Complication; Early Mobilization

Keywords

ICU-mobility-scale

Outcome Measures

Primary Outcomes (1)

• Predictive validity of the IMS

  Predictive validity of the IMS-score performed in the first 24 hours after admission to the ICU for the length of stay in the ICU

  approximate 28 days (till ICU discharge)

Secondary Outcomes (11)

• ICU mortality

  approximate 28 days (till ICU discharge)

• Duration of mechanical ventilation

  approximate 28 days (till ICU discharge)

• Discharge location

  approximate at 28 days (at hospital discharge)

• MRC Score

  approximate 28 days (till ICU discharge)

• Muscle strength

  approximate 28 days (till ICU discharge)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study includes intensive care patients who are treated by the Clinic for Anesthesiology with focus on surgical intensive care medicine at the Charité - Universitätsmedizin Berlin for an expected period of more than 24 hours, who are at least 18 years old and receive ventilation support.

You may qualify if:

• Critically ill adults (age: ≥ 18 years)
• Expected length of stay in ICU \> 24h
• Ventilation support

You may not qualify if:

• Patients transferred from other ICUs
• Patients with pre-existing functional limitations
• Patients with functional limitations due to the admission diagnosis (e.g. stroke. with hemiparesis)

Sponsors & Collaborators

• Charite University, Berlin, Germany: lead

Study Sites (1)

Charité - Univiversitätsmedizin Berlin

Berlin, State of Berlin, 10117, Germany

Location

MeSH Terms

Conditions

Muscle Weakness; Critical Illness

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Disease Attributes

Study Officials

• Stefan J Schaller, MD

  Charite University, Berlin, Germany

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Deputy Clinical Director

Study Record Dates

• First Submitted: August 17, 2022
• First Posted: October 24, 2022
• Study Start: January 24, 2023
• Primary Completion: November 11, 2024
• Study Completion: February 20, 2025
• Last Updated: April 24, 2025

Record last verified: 2025-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF
• Time Frame: After publication of scientific manuscript.
• Access Criteria: Deidentified data can be requested on reasonable scientific request.

Locations

DE (1)