NCT05590026

Brief Summary

American Society of Anaesthesiologist physical status II-III, aged between 2, 12 patients which underwent open cardiac surgery will recruited to this study. These subjects will Ultrasound (USG) guided erector spinae block will perform at T6 level (bilaterally) and pectointercostal plane block at 4-5 intercostal space to the all patient under general anaesthesia. Totally bupivacaine %0.25 2.5 mg/kg will use blocks. 2 ml %0.25 bupivacain will apply to the chest tube area at the end of surgery. 0.1 microgram/kg morphine will apply intravenously at last 30 minutes of surgery postoperative analgesia to all patients. Postoperative pain and agitation assessment will perform with FLACC and Watcha scores

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for phase_4 postoperative-pain

Timeline
Completed

Started Oct 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 15, 2022

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

October 18, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 21, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2023

Completed
Last Updated

April 27, 2023

Status Verified

October 1, 2022

Enrollment Period

10 months

First QC Date

October 18, 2022

Last Update Submit

April 26, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Postoperative analgesia

    Postoperative analgesia will asses Face, Legs, Activity, Cry, Consolability (FLACC) score in (Postanesthesia care unit) PACU till the 24th hours postoperatively. FLACC score reflects pain score between 0-10. 0 means zero pain, 10 means worse pain score

    24 hours in Postanesthesia care unit (PACU)

  • Postoperative morphine consumption

    Postoperative morphine consumption will record till the postoperative 24 th hours

    24 hours in Postanesthesia care unit (PACU)

Secondary Outcomes (1)

  • Postoperative agitation

    First 24 hours at Postanesthesia care unit (PACU)

Study Arms (2)

Pectointercostal and ESP block

ACTIVE COMPARATOR

Pectointercostal and ESP block will apply to the children after intubation. Totally bupivacain %0.25, 2.5 mg/kg will apply.

Drug: Pectointercostal and ESP block

No Block

PLACEBO COMPARATOR

No block will apply to the patient

Drug: Pectointercostal and ESP block

Interventions

Both Pectointercostal at between 4th and 5th costa and ESP block will apply at thoracal 6 level to the patient.

Also known as: Fascia plane blocks
No BlockPectointercostal and ESP block

Eligibility Criteria

Age2 Years - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Ages between 2-12 years
  • ASA II-III children
  • The children who undergoing open heart surgery

You may not qualify if:

  • Coagulopaty
  • Allergy of local anesthetic
  • Liver and renal failure
  • Obesity (BMI \>35kg/m2)
  • Infection at the block area

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cukurova University

Adana, 01380, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Officials

  • Ebru Biricik

    Cukurova University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 18, 2022

First Posted

October 21, 2022

Study Start

October 15, 2022

Primary Completion

August 15, 2023

Study Completion

August 15, 2023

Last Updated

April 27, 2023

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations