Mild Head Trauma in the Emergency Room: Assessment of the Risk of Intracranial Hemorrhage in Patients Receving Platelet Inhibitors.

NCT05589103 | Unknown

• 1 other identifier: 7409
• Study Type: observational
• Target: 1,692
• Locations: 1 country
• Sites: 1

Brief Summary

The clinical signs presented by a patient with a mild head injury are highly variable but remain strongly predictive of brain damage. The reference examination for the diagnosis of post-traumatic intracranial hemorrhage is currently the cerebral scanner without injection of contrast medium. Magnetic resonance imaging (MRI) tends to surpass CT in equipped centers, except for suspected bone lesions. The time required to perform brain imaging depends on the patient's clinical condition, comorbidities and treatments. The responsibility of antiplatelet agents in post-traumatic intracranial hemorrhage is currently discussed, particularly with aspirin. The hypothesis is that there is no significant difference in the proportion of intracranial hemorrhage in patients on antiplatelet agents after mild head trauma, in the absence of other factors favoring the occurrence of intracranial hemorrhage.

Conditions

Head Trauma Injury

Keywords

Head Trauma Injury; Head Trauma; Traumatic Intracranial Hemorrhage; Antiaggregants, Platelet

Outcome Measures

Primary Outcomes (1)

• Propensity score on the factors influencing the taking of antiplatelet agents.

  Files analysed retrospectively from January 01, 2017 to December 31, 2017 will be examined

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient (≥18 years old) victim of mild head trauma visiting the emergency room of the Strasbourg University Hospital during 2017.

You may qualify if:

• Adult patient (≥18 years old)
• Visit to the emergency room of the Strasbourg University Hospital during 2017
• Victim of mild head trauma
• Patient who has given their consent to the reuse of their data for the purposes of this research.
• Patient who expressed their opposition to participating in the study
• Subject under safeguard of justice
• Subject under guardianship or curatorship
• Patient on anticoagulant
• Non-isolated head trauma (AVP, fall greater than 6 meters, etc.)

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service d'accueil des urgences - CHU de Strasbourg - France

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Craniocerebral Trauma; Intracranial Hemorrhage, Traumatic

Condition Hierarchy (Ancestors)

Trauma, Nervous System; Nervous System Diseases; Wounds and Injuries; Intracranial Hemorrhages; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Florent BAICRY, MD

CONTACT

33 3 69 55 03 86; florent.baicry@chru-strasbourg.fr

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 17, 2022
• First Posted: October 21, 2022
• Study Start: January 1, 2020
• Primary Completion: December 1, 2022
• Study Completion: December 31, 2022
• Last Updated: October 21, 2022

Record last verified: 2022-10

Locations

FR (1)