NCT05588947

Brief Summary

Take Charge is a novel, community-based treatment for stroke developed to harness a person's self-determination. Two prior clinical trials with 572 stroke survivors showed that Take Charge improves quality of life, independence, and social participation up to a year after stroke. Take Charge has also been shown to be overall cost-saving to the health system and is a useful adjunct to standard care after stroke. Because of the COVID-19 pandemic, a lot of healthcare has moved into a telehealth approach. The simplicity of Take Charge may lend itself to being effective if delivered by telehealth, allowing greater access for people with stroke in rural communities. Improving the care we provide in underserved regions of the country is important to help the health of Canadians. We are proposing a new study, working closely with the researchers who ran the previous Take Charge studies. The goal of this feasibility clinical trial is to learn about Tele-Take Charge in adults with stroke who live in Southern Alberta. The main questions it aims to answer are:

  • is delivering Take Charge by telehealth feasible?
  • is Take Charge by telehealth acceptable to this population? Participants will meet with facilitators online via Zoom at 4 to 16 weeks after stroke, and be randomized to receive either:
  • two Tele-Take Charge sessions six weeks apart
  • one control tele-education session. Researchers will compare the Tele-Take Charge and control groups to see if there are any differences in outcome measures. these differences will help researchers to estimate the number of participants that will be needed for a larger, multi-centred effectiveness trial.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2022

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2022

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

October 17, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 20, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 10, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 10, 2023

Completed
Last Updated

October 20, 2022

Status Verified

October 1, 2022

Enrollment Period

1.1 years

First QC Date

October 17, 2022

Last Update Submit

October 17, 2022

Conditions

Keywords

self-determinationrehabilitation

Outcome Measures

Primary Outcomes (1)

  • Rate of recruitment

    Number of participants recruited per month

    12 months

Secondary Outcomes (9)

  • Eligibility

    12 months

  • Treatment adherence

    12 months

  • Acceptability of Tele-TaCAS

    2 weeks after receiving Tele-TaCAS

  • Health-related quality of life

    6 and 12 months after stroke

  • Independence - modified Rankin scale 0 to 2

    6 and 12 months after stroke

  • +4 more secondary outcomes

Study Arms (2)

Tele-TaCAS

EXPERIMENTAL

Two Take Charge sessions delivered by telehealth six weeks apart, the first being at 2 to 16 weeks after stroke, the earliest possible time after discharge to the community.

Other: Take Charge session

Control

ACTIVE COMPARATOR

Life After Stroke: Survivor Stories video played by telehealth at 2 to 16 weeks after stroke, the earliest possible time after discharge to the community.

Other: Active Control

Interventions

A 'talk therapy' session designed to harness the person's self-determination, re-establishing purpose, identity, autonomy, and skills to Take Charge of their recovery after stroke

Tele-TaCAS

Life After Stroke educational video

Control

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Discharged with diagnosis of stroke to non-institutionalised community living situation
  • Answering 'No' to the question 'Are you fully recovered from your stroke?' (i.e., modified Rankin score \[mRS\] must be \> 0)
  • Able to access video calling with a smartphone, computer, or other device

You may not qualify if:

  • Major comorbid illness that would dictate functional outcome at 12 months or life expectancy \< 12 months
  • Pre-stroke dependency (mRS \> 2 before index stroke)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Dr Vernon Fanning CareWest Rehabilitation Centre

Calgary, Canada

Location

Foothills Medical Centre

Calgary, Canada

Location

Related Links

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Vivian WY Fu, PhD

CONTACT

Sean P Dukelow, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Prospective Randomized Controlled Open Blinded Endpoint Feasibility Trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 17, 2022

First Posted

October 20, 2022

Study Start

October 10, 2022

Primary Completion

November 10, 2023

Study Completion

November 10, 2023

Last Updated

October 20, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations