NCT05587933

Brief Summary

In this study investigators aim to evaluate gallbladder ejection fraction as a predictor for cholecystectomy.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 24, 2022

Completed
26 days until next milestone

First Posted

Study publicly available on registry

October 20, 2022

Completed
5 days until next milestone

Study Start

First participant enrolled

October 25, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

October 20, 2022

Status Verified

October 1, 2022

Enrollment Period

6 months

First QC Date

September 24, 2022

Last Update Submit

October 18, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Rate of quality of life improvment after cholecystectomy according to ROME IV criteria

    abdominal pain, nausea and vomiting

    6 months

Study Arms (1)

operative

EXPERIMENTAL
Procedure: cholecystectomyDrug: Antispasmodic

Interventions

cholecystectomy

operative

Antispasmodic

operative

Eligibility Criteria

Age12 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients older than 14 years of age
  • food-related abdominal pain
  • normal gallbladder ultrasound (US)
  • GB EF 80% and greater or 35% and less on HIDA scan with CCK injection

You may not qualify if:

  • Patients younger than 14 years old
  • Patients with the positive US defined as the presence of gallstones, gallbladder wall thickening (\> 4 mm), pericholecystic fluid, sludge, or polyps
  • Normal GB EF

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Acalculous Cholecystitis

Interventions

CholecystectomyParasympatholytics

Condition Hierarchy (Ancestors)

CholecystitisGallbladder DiseasesBiliary Tract DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Biliary Tract Surgical ProceduresDigestive System Surgical ProceduresSurgical Procedures, OperativeAutonomic AgentsPeripheral Nervous System AgentsPhysiological Effects of DrugsPharmacologic ActionsChemical Actions and Uses

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
General surgery resident

Study Record Dates

First Submitted

September 24, 2022

First Posted

October 20, 2022

Study Start

October 25, 2022

Primary Completion

May 1, 2023

Study Completion

July 1, 2023

Last Updated

October 20, 2022

Record last verified: 2022-10