NCT05587608

Brief Summary

Ultrasound-guided combined thoracic segmental spinal epidural anesthesia in comparison with general anesthesia in upper abdominal and breast surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
63

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2022

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

October 14, 2022

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 14, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 14, 2022

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 20, 2022

Completed
Last Updated

November 2, 2022

Status Verified

October 1, 2022

Enrollment Period

8 months

First QC Date

October 14, 2022

Last Update Submit

October 29, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • MAP

    mean arterial pressure

    Change from Baseline Systolic Blood Pressure at one day post operative

Study Arms (2)

ultrasound-guided thoracic segmental spinal group

ACTIVE COMPARATOR

given ultrasound-guided thoracic segmental spinal heavy Marcaine plus 25 ug fentanyl at the level of T10 interlaminar space.

Procedure: combined thoracic segmental spinal epidural anesthesia

General anesthesia group

NO INTERVENTION

General anesthesia (control)

Interventions

ultrasound guided thoracic segmental spinal anesthesia at the level of T10 interlaminar space , patients will be in sitting position, spinal needle is then introduced through the epidural needle not more than 0.5 cm beyond the Dura matter. 2cc of heavy Marcaine plus 25 ug fentanyl are injected through the spinal needle.

ultrasound-guided thoracic segmental spinal group

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • All upper abdominal and laparoscopic surgeries
  • ASA I-III CLASS
  • Age between 18 and 60

You may not qualify if:

  • Contraindication of regional ASA More than III Age less than18 or more than 60 Psychological troubles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt

Asyut, 0020, Egypt

Location

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
clinical lecturer

Study Record Dates

First Submitted

October 14, 2022

First Posted

October 20, 2022

Study Start

March 1, 2022

Primary Completion

October 14, 2022

Study Completion

October 14, 2022

Last Updated

November 2, 2022

Record last verified: 2022-10

Locations