Boost Intentions and Facilitate Action to Promote COVID-19 Booster Take-up

NCT05586204 | Completed

• 1 other identifier: covidbooster1
• Study Type: interventional
• Target: 154,977
• Locations: 1 country
• Sites: 1

Brief Summary

This is a prospective randomized clinical trial evaluating how behaviorally-informed outreach text messages affect the take-up of bivalent COVID-19 booster. The investigators will test the impact of sending text reminders as well as the importance of elevating vaccination intentions, facilitating action, and their combination.

Conditions

COVID-19; Vaccines

Keywords

COVID19; Vaccines; Text-messages; Patient Outreach; Behavioral Science

Outcome Measures

Primary Outcomes (2)

• booster take-up in 2 weeks

  Whether people receive the bivalent booster at any location reporting to the California Immunization Registry (CAIR)

  2 weeks after getting the text message

• booster take-up in 4 weeks

  Whether people receive the bivalent booster at any location reporting to CAIR

  4 weeks after getting the text message

Secondary Outcomes (3)

• booster take-up at UCLA/CVS in 2 weeks

  2 weeks after getting the text message

• booster take-up at UCLA/CVS in 4 weeks

  4 weeks after getting the text message

• Link click rate in 1 week

  1 week after getting the text message

Study Arms (6)

Facilitate action narrowly

EXPERIMENTAL

Behavioral: Eligibility reminder; Behavioral: Link to a narrow set of vaccine venues

Facilitate action broadly

EXPERIMENTAL

Behavioral: Eligibility reminder; Behavioral: Link to a broad set of vaccine venues

Boost intentions only

EXPERIMENTAL

Behavioral: Eligibility reminder; Behavioral: Doctors' recommendation and value of vaccine

Boost intentions and facilitate action narrowly

EXPERIMENTAL

Behavioral: Eligibility reminder; Behavioral: Link to a narrow set of vaccine venues; Behavioral: Doctors' recommendation and value of vaccine

Boost intentions and facilitate action broadly

EXPERIMENTAL

Behavioral: Eligibility reminder; Behavioral: Link to a broad set of vaccine venues; Behavioral: Doctors' recommendation and value of vaccine

Holdout

NO INTERVENTION

Interventions

Eligibility reminder BEHAVIORAL

Patients will receive a reminder of their eligibility for the bivalent COVID-19 booster

Boost intentions and facilitate action broadly; Boost intentions and facilitate action narrowly; Boost intentions only; Facilitate action broadly; Facilitate action narrowly

Link to a narrow set of vaccine venues BEHAVIORAL

The reminder will encourage people to claim their dose today by booking an appointment. It will contain a link to schedule a booster appointment at UCLA Health and a link to CVS pharmacy

Boost intentions and facilitate action narrowly; Facilitate action narrowly

Link to a broad set of vaccine venues BEHAVIORAL

The reminder will encourage people to claim their dose today by booking an appointment. It will contain a link to schedule a booster appointment at UCLA Health and a link to vaccine.gov (where people can find a wide set of local pharmacies that carry the bivalent booster).

Boost intentions and facilitate action broadly; Facilitate action broadly

Doctors' recommendation and value of vaccine BEHAVIORAL

The reminder will contain information about the value of the bivalent booster and doctors' recommendation to get it

Boost intentions and facilitate action broadly; Boost intentions and facilitate action narrowly; Boost intentions only

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged 18 or above
• Have a mobile phone number or SMS-capable phone number in UCLA Health's database
• Having completed a COVID-19 vaccine primary series based on CAIR data
• Last COVID-19 vaccine shot (including booster shot) occurred at least two months before the date when patient list are pulled in preparation for the trial, based on CAIR data. The last two criteria are meant to identify patients who are eligible for the bivalent booster.

You may not qualify if:

• Patients who have received the bivalent booster anywhere (based on CAIR data) before the day they receive the text message
• Patients who have already scheduled appointments at UCLA Health for getting the bivalent booster before the day they receive the text message

Sponsors & Collaborators

• University of California, Los Angeles: lead

Study Sites (1)

UCLA Health Department of Medicine, Quality Office

Los Angeles, California, 90095, United States

Location

Related Publications (1)

• Milkman KL, Patel MS, Gandhi L, Graci HN, Gromet DM, Ho H, Kay JS, Lee TW, Akinola M, Beshears J, Bogard JE, Buttenheim A, Chabris CF, Chapman GB, Choi JJ, Dai H, Fox CR, Goren A, Hilchey MD, Hmurovic J, John LK, Karlan D, Kim M, Laibson D, Lamberton C, Madrian BC, Meyer MN, Modanu M, Nam J, Rogers T, Rondina R, Saccardo S, Shermohammed M, Soman D, Sparks J, Warren C, Weber M, Berman R, Evans CN, Snider CK, Tsukayama E, Van den Bulte C, Volpp KG, Duckworth AL. A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor's appointment. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2101165118. doi: 10.1073/pnas.2101165118.

  PMID: 33926993 BACKGROUND

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 17, 2022
• First Posted: October 19, 2022
• Study Start: October 18, 2022
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2023
• Last Updated: December 9, 2024

Record last verified: 2024-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)