Sarcopenia After Bariatric Surgery in Older Patients: a Cohort Study
SABO
1 other identifier
observational
100
1 country
1
Brief Summary
The retrospective cohort study will compare the prevalence of sarcopenia and associated factors between older patients who have undergone bariatric surgery and older patients with obesity without previous bariatric surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 3, 2022
CompletedFirst Submitted
Initial submission to the registry
October 12, 2022
CompletedFirst Posted
Study publicly available on registry
October 17, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 14, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
July 14, 2024
CompletedFebruary 25, 2025
October 1, 2024
1.8 years
October 12, 2022
February 21, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
The number of older patients with sarcopenia after bariatric surgery compared to non-surgical control patients.
a) Sarcopenia will be classified according to the criteria form the European Working Group on Sarcopenia in Older People revised guidelines (EWGSOP2) based on skeletal muscle mass, muscle strength and physical performance criteria.
At least one year post surgery
Secondary Outcomes (3)
1. Appendicular skeletal muscle mass older of patients after bariatric surgery compared to non-surgical control patients
At least one year post surgery
2. The prevalence of nutrient deficiencies in older patients after bariatric surgery compared to non-surgical control patients.
At least one year post surgery
3. Markers of chronic systemic inflammation in older patients after bariatric surgery compared to non-surgical control patients
At least one year post surgery
Study Arms (2)
Cohort 1
Cohort 1: Older patients with overweight, obesity after bariatric surgery
Cohort 2
Cohort 2: Older patients with overweight, obesity without bariatric surgery
Interventions
Eligibility Criteria
Subjects with overweight, obesity or after bariatric surgery
You may qualify if:
- Signed informed consent
- Age 65 years or older
- Cohort 1 (exposed): Previous bariatric surgery for obesity at least 1 one year ago
- Cohort 2 (unexposed): No previous weight loss surgery
You may not qualify if:
- Current diagnosis of cancer
- Advanced organ failure, including chronic kidney disease Stage 5, liver cirrhosis Stage 3, intestinal failure, heart failure stage D, or chronic obstructive pulmonary disease stage 4.
- Immobility
- Neuromuscular degenerative conditions
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Obesity Clinic University Hospitals Leuven
Leuven, 3000, Belgium
Related Publications (1)
Eksteen G, Vanuytsel T, Vangoitsenhoven R, Mertens A, Lannoo M, De Leus E, Van der Schueren B, Matthys C. Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery. J Cachexia Sarcopenia Muscle. 2025 Jun;16(3):e13839. doi: 10.1002/jcsm.13839.
PMID: 40468919DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 12, 2022
First Posted
October 17, 2022
Study Start
October 3, 2022
Primary Completion
July 14, 2024
Study Completion
July 14, 2024
Last Updated
February 25, 2025
Record last verified: 2024-10
Data Sharing
- IPD Sharing
- Will not share