NCT05580913

Brief Summary

This research study is comparing the effect of traditional standardized, subjective auto-regulated, and objective auto-regulated resistance training on physiological adaptations and performance measures in adults aged 50 years or older. Traditional standardized resistance training involves prescribing resistance training as a percentage of an individual's one-repetition maximum (i.e., the maximal weight they can lift one time). Auto-regulated resistance training involves adjusting resistance training based on an individual's performance during the session. Subjective auto-regulation involves the resistance trainee providing a subjective rating of perceived exertion based on repetitions in reserve (on a scale from 1 - 10) to adjust the resistance training prescription. A rating of perceived exertion of 10 would mean that the resistance trainee believes that they have provided maximal effort and believes that they could not have performed an additional repetition during the set nor increased the load. Objective auto-regulation involves adjusting the resistance training prescription from a linear position transducer (a device that has a string that attaches to the barbell and provides a velocity value on each repetition). A slower velocity value means a higher perceived exertion and load used, whereas a faster velocity value means a lower perceived exertion and load used.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 11, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 14, 2022

Completed
1 day until next milestone

Study Start

First participant enrolled

October 15, 2022

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2023

Completed
Last Updated

May 29, 2024

Status Verified

May 1, 2024

Enrollment Period

11 months

First QC Date

October 11, 2022

Last Update Submit

May 24, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Change from baseline in bench press strength

    baseline, 12 weeks

  • Change from baseline in squat strength

    baseline, 12 weeks

Secondary Outcomes (6)

  • Change from baseline in muscle thickness

    Baseline, 12 weeks

  • Change from baseline in knee extension strength

    Baseline, 12 weeks

  • Change from baseline for time to sit and stand from a chair five times

    Baseline, 12 weeks

  • Change from baseline in time to complete the "timed up and go" (TUG) test

    Baseline, 12 weeks

  • Change from baseline in time to climb 10 stairs

    Baseline, 12 weeks

  • +1 more secondary outcomes

Study Arms (3)

Subjective auto-regulation training

EXPERIMENTAL

Participants complete their resistance-training sets to termination based on rating of perceived exertion

Behavioral: Resistance training

Objective auto-regulation training

EXPERIMENTAL

Participants complete their resistance-training sets to termination based on reaching a critical slow velocity

Behavioral: Resistance training

Traditional standardized training

ACTIVE COMPARATOR

Participants complete their resistance-training sets by lifting a prescribed percentage of their estimated one-repetition maximum (as determined from baseline four-repetition maximum strength testing)

Behavioral: Resistance training

Interventions

12 weeks of resistance-training performed two times per week

Objective auto-regulation trainingSubjective auto-regulation trainingTraditional standardized training

Eligibility Criteria

Age50 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Males and females 50 years of age or greater

You may not qualify if:

  • Inability to safely perform squat and bench press exercises as determined by the Get Active Questionnaire

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Saskatchewan

Saskatoon, Saskatchewan, S7N5B2, Canada

Location

MeSH Terms

Conditions

Sarcopenia

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and Symptoms

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

October 11, 2022

First Posted

October 14, 2022

Study Start

October 15, 2022

Primary Completion

August 31, 2023

Study Completion

August 31, 2023

Last Updated

May 29, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations