Trials Sponsors Conditions Drugs Pricing

Conditions

Lens Subluxation or Dislocation Marfan Syndrome

Outcome Measures

Primary Outcomes (7)

Uncorrected distance visual acuity
1 month postoperatively
Uncorrected distance visual acuity
3 month postoperatively
Corrected distance visual acuity
1 month postoperatively
Corrected distance visual acuity
3 month postoperatively
intraocular pressure
1 month postoperatively
intraocular pressure
3 month postoperatively
postoperative complication

Secondary Outcomes (4)

Postoperative astigmatism and astigmatism axial of cornea
1 month postoperatively
Postoperative astigmatism and astigmatism axial of cornea
3 month postoperatively
endothelial cell count
1 month postoperatively
endothelial cell count
3 month postoperatively

Study Arms (2)

posterior chamber intraocular lens(IOL) implantation with a Cionni capsular tension ring (CTR)

Procedure: surgical treatment of Marfan Syndrome with subluxation lens

sutured scleral fixation of posterior chamber IOL/ posterior chamber IOL and CTR

Procedure: surgical treatment of Marfan Syndrome with subluxation lens

Interventions

surgical treatment of Marfan Syndrome with subluxation lensProcedure

different surgical treatment of Marfan Syndrome with subluxation lens

posterior chamber intraocular lens(IOL) implantation with a Cionni capsular tension ring (CTR)sutured scleral fixation of posterior chamber IOL/ posterior chamber IOL and CTR

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age8 Years - 55 Years

Sexall

Healthy VolunteersNo

Age GroupsChild (0-17), Adult (18-64)

Sampling MethodNon-Probability Sample

Study Population

Patients with lens dislocation of Marfan syndrome who accepted different surgical treatments

You may qualify if:

Patients diagnosed with MFS according to the revised Ghent etiology.

Sponsors & Collaborators

Second Affiliated Hospital, Zhejiang University, School of Medicine
Otherlead

Study Sites (1)

Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, China

MeSH Terms

Conditions

Marfan SyndromeLens Subluxation

Condition Hierarchy (Ancestors)

Bone Diseases, DevelopmentalBone DiseasesMusculoskeletal DiseasesHeart Defects, CongenitalCardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesAbnormalities, MultipleCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesGenetic Diseases, InbornConnective Tissue Diseases

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: RETROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

October 11, 2022

First Posted

October 13, 2022

Study Start

January 1, 2016

Actual (reported)

Primary Completion

November 1, 2022

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Surgical Treatment of Marfan Syndrome With Subluxation Lens

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (7)

Secondary Outcomes (4)

Study Arms (2)

posterior chamber intraocular lens(IOL) implantation with a Cionni capsular tension ring (CTR)

sutured scleral fixation of posterior chamber IOL/ posterior chamber IOL and CTR

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (7)

Secondary Outcomes (4)

Study Arms (2)

posterior chamber intraocular lens(IOL) implantation with a Cionni capsular tension ring (CTR)

sutured scleral fixation of posterior chamber IOL/ posterior chamber IOL and CTR

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations