Combined Phacoemulsification and Diode Laser Therapy in Chronic Angle Closure Glaucoma
1 other identifier
interventional
88
1 country
1
Brief Summary
comparing different types of cuclophotocoagulation with cataract extraction to cataract extraction and goniocynechiolysis in cases of chronic angle closure glaucoma
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Aug 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 11, 2022
CompletedFirst Submitted
Initial submission to the registry
October 8, 2022
CompletedFirst Posted
Study publicly available on registry
October 12, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2023
CompletedAugust 30, 2023
August 1, 2023
1.1 years
October 8, 2022
August 29, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
the percentage of intraocular pressure change
measuring the intraocular pressure after 1M, 3M and 6M
6 Months
Secondary Outcomes (1)
percent change of antiglaucoma medications
6 Months
Study Arms (4)
A:phaco+MP-TSCPC
EXPERIMENTAL22 patients with primary angle closure glaucoma will undergo phacoemulsification and micropulse cyclophotocoagulation
B:phaco+TSCPC
EXPERIMENTAL22 patients with primary angle closure glaucoma will undergo phaco and transscleral cyclophotocoagulation
C:phaco+endocyclophotocoagulation
EXPERIMENTAL22 patients with primary angle closure glaucoma will undergo phaco and endocyclophotocoagulation after cataract removal
D:phaco GSL
EXPERIMENTAL22 patients with primary angle closure glaucoma will undergo phaco and goniosynechiolysis
Interventions
The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.
The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.
phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction
phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.
Eligibility Criteria
You may qualify if:
- Patients between 20 to 70 years
- chronic angle closure glaucoma
You may not qualify if:
- Patients in acute attack of angle closure.
- Patients with previous filtering surgery or cycloablative procedure
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Kasr Alainy
Cairo, 11562, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Ahmed Abdelrahman, PhD
kasr alainy
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer
Study Record Dates
First Submitted
October 8, 2022
First Posted
October 12, 2022
Study Start
August 11, 2022
Primary Completion
October 1, 2023
Study Completion
December 1, 2023
Last Updated
August 30, 2023
Record last verified: 2023-08
Data Sharing
- IPD Sharing
- Will not share