Comparison of the Efficacy of Tidal Volume Breathing and Vital Capacity Breathing During High-flow Nasal Oxygen
1 other identifier
interventional
58
1 country
1
Brief Summary
The purpose of this study is to compare the preoxygenation efficacy of tidal volume breathing and vital capacity breathing.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Oct 2022
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2022
CompletedFirst Submitted
Initial submission to the registry
October 6, 2022
CompletedFirst Posted
Study publicly available on registry
October 7, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 22, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
September 22, 2025
CompletedJune 9, 2026
June 1, 2026
3 years
October 6, 2022
June 4, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
End-tidal O2
End-tidal O2 will be monitored continuously before anesthetic induction.
for 10 minutes before anesthetic induction. At Day 0.
Study Arms (2)
Tidal volume breathing technique
EXPERIMENTALHigh-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system before anesthetic induction. Tidal volume breathing will be applied. Pulse oximetry, end-tidal O2, and oxygen reserve index will be monitored continuously.
Vital capacity breathing technique
ACTIVE COMPARATORHigh-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system before anesthetic induction. Vital capacity breathing will be applied. Pulse oximetry, end-tidal O2, and oxygen reserve index will be monitored continuously.
Interventions
High-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system before anesthetic induction. Tidal volume breathing will be applied. Pulse oximetry, end-tidal O2, and oxygen reserve index will be monitored continuously.
High-flow nasal oxygen will be applied to the patients through nasal openings using Optiflow system before anesthetic induction. Vital capacity breathing will be applied. Pulse oximetry, end-tidal O2, and oxygen reserve index will be monitored continuously.
Eligibility Criteria
You may qualify if:
- Adult patients 20 years of age or older who are planning to undergo surgery under general anesthesia
You may not qualify if:
- basal skull fracture, 2번 - facial anomaly, 3번 - consciousness disorder, 4번 - Risk of aspiration
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Yonsei University Health System, Severance Hospital
Seoul, South Korea
Study Officials
- PRINCIPAL INVESTIGATOR
Hyun Joo Kim
Severance Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 6, 2022
First Posted
October 7, 2022
Study Start
October 1, 2022
Primary Completion
September 22, 2025
Study Completion
September 22, 2025
Last Updated
June 9, 2026
Record last verified: 2026-06
Data Sharing
- IPD Sharing
- Will not share