Personalized Computerized Training Program for Cognitive Dysfunction After COVID-19

NCT05571852 | Completed

• 1 other identifier: UANebrija
• Study Type: interventional
• Target: 73
• Locations: 1 country
• Sites: 1

Brief Summary

This before-and-after study aims to evaluate the usefulness and efficacy of a personalized computerized cognitive training (CCT) to improve cognitive function among people with post-acute sequelae of COVID-19 (PASC).

Conditions

Post-Acute COVID-19; Long COVID

Keywords

Long COVID; Computerized Cognitive Training; Post-Acute Sequeale of COVID-19; Cognitive Dysfunction; Brain Fog

Outcome Measures

Primary Outcomes (1)

• Cognitive Gains

  The difference in scores between the initial and final assessments as evaluated by the Cognitive Assessment Battery (CAB)™ PRO

  8 weeks

Secondary Outcomes (1)

• Intensity of the training

  8 weeks

Study Arms (1)

Computerized Cognitive Training

EXPERIMENTAL

Participants will be asked to complete short sessions of around 10 minutes each consisting of a variety of games designed to train the five cognitive skills (attention, memory, coordination, reasoning and perception). Each training session include two games selected among a pool of 12 different games. Participants will be asked to complete a training lasting for 8 weeks in which they could access the training platform as frequently as they wanted.

Device: CogniFit's CCT Post COVID-19

Interventions

CogniFit's CCT Post COVID-19 DEVICE

The computerized cognitive training (CCT) program is tailored to each person's specific cognitive strengths and weaknesses detected in the Cognitive Assessment Battery (CAB)™ PRO (CogniFit Inc., San Francisco, US; https://www.cognifit.com/cab) by a patented Individualized Training System™ (ITS) software.

Computerized Cognitive Training

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults (older than 18 years old).
• History of infection with COVID-19 at least 3 months prior to expression of interest.
• Presence of self-perceived cognitive dysfunction associated with PACS (concentration problems or brain fog).

You may not qualify if:

• Completion of less than 10 training sessions.
• Not completing the final evaluation after the 8-week training period.

Sponsors & Collaborators

• Universidad Antonio de Nebrija: lead

Study Sites (1)

Universidad Nebrija

Madrid, Spain

Location

Related Publications (1)

• Dunabeitia JA, Mera F, Baro O, Jadad-Garcia T, Jadad AR. Personalized Computerized Training for Cognitive Dysfunction after COVID-19: A Before-and-After Feasibility Pilot Study. Int J Environ Res Public Health. 2023 Feb 10;20(4):3100. doi: 10.3390/ijerph20043100.

  PMID: 36833793 DERIVED

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome; Cognitive Dysfunction; Mental Fatigue

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Fatigue; Signs and Symptoms; Behavioral Symptoms; Behavior

Study Officials

• Jon Andoni Duñabeitia

  Universidad Nebrija

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 3, 2022
• First Posted: October 7, 2022
• Study Start: December 1, 2021
• Primary Completion: February 28, 2022
• Study Completion: February 28, 2022
• Last Updated: October 7, 2022

Record last verified: 2022-10

Locations

ES (1)