NCT05569330

Brief Summary

Effect of aerosol flitration and removal on typical infectious diseases such as upper respiratory tract infectinos is studied in day care. Many filtration methods such as filters and electrical filtering are used to remove aerosol particles from room air.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
92

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 28, 2022

Completed
8 days until next milestone

First Posted

Study publicly available on registry

October 6, 2022

Completed
26 days until next milestone

Study Start

First participant enrolled

November 1, 2022

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2024

Completed
Last Updated

May 11, 2023

Status Verified

May 1, 2023

Enrollment Period

1.5 years

First QC Date

September 28, 2022

Last Update Submit

May 10, 2023

Conditions

Upper Respiratory Tract InfectionDiarrhea

Outcome Measures

Primary Outcomes (1)

  • Incident infections

    Incident infections among subjects

    During the study periods 11/22-4/23 and 11/23-4/24. These are identical for every subject.

Secondary Outcomes (1)

  • Days absent from work

    During the study periods 11/22-4/23 and 11/23-4/24. These are identical for every subject.

Study Arms (2)

Arm 1

OTHER

Two of the four participating day care units are allocated in arm 1

Other: Air purification

Arm 2

OTHER

Two of the four participating day care units are allocated in arm 2

Other: Air purification

Interventions

Air purificationOTHER

Aerosol particles are removed from room air by several methods

Arm 1Arm 2

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is expected to be in the same day care unit for the duration of the study

You may not qualify if:

  • Subject is known not to be in the same day care unit for the duration of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

City of Helsinki Day care

Helsinki, Finland

Location

MeSH Terms

Conditions

Respiratory Tract InfectionsDiarrhea

Condition Hierarchy (Ancestors)

InfectionsRespiratory Tract DiseasesSigns and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Ville Vartiainen, MD, PhD

    Helsinki University Central Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD, MSc, researhcer

Study Record Dates

First Submitted

September 28, 2022

First Posted

October 6, 2022

Study Start

November 1, 2022

Primary Completion

April 30, 2024

Study Completion

April 30, 2024

Last Updated

May 11, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations

FI(1)