Outcome of Cardiomyopathic Adults Admission in ICU.

NCT05567445 | Unknown

• 1 other identifier: Cardiomyopathy in ICU.
• Study Type: observational
• Target: 45
• Locations: 0 countries
• Sites: N/A

Brief Summary

To study the outcome of the cardiac function, and clinical status of the patiants with cardiomyopathy who are admitted in the I.C.U.

Conditions

Cardiomyopathies

Outcome Measures

Primary Outcomes (4)

• Effect on E.F.

  Degree of impairement of E.F.

  through study completion, an average of 1 year

• Effect on renal function

  Who developed renal impairement, and its effect on cardiac function.

  through study completion, an average of 1 year

• Sepsis

  Who developed sepsis and its effect on cardiac function.

  through study completion, an average of 1 year

• Effect on liver function

  Who suffer liver function impairement, improvement or deteroriation

  through study completion, an average of 1 year

Interventions

Echocardiography, CBC, Liver function, kideny function DIAGNOSTIC_TEST

Echocardiography, AST, ALT, UREA,CREAT. , CBC,may blood cultures.

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Cardiomyopathic patiants with the previous inclusion criteria.

You may qualify if:

• Cardiomyopathic patiants admitted with heart failure diagonsed clinicaly , by Echocardiograph , or by ECG.
• Dilated cardiomyopathy\[ Unknown, Uremic cardiomyopathy, Post-partum, Ishemic\].
• Hypertrophic cardiomyopathy.
• Acute heart failure caused by A.C.S. , Toxic myocardititis.

You may not qualify if:

• Heart failure due to valvular heart disease.
• Heart failure caused by hypertension.
• patiant with COPD

Sponsors & Collaborators

• Assiut University: lead

Related Publications (7)

• Seferovic PM, Polovina M, Bauersachs J, Arad M, Ben Gal T, Lund LH, Felix SB, Arbustini E, Caforio ALP, Farmakis D, Filippatos GS, Gialafos E, Kanjuh V, Krljanac G, Limongelli G, Linhart A, Lyon AR, Maksimovic R, Milicic D, Milinkovic I, Noutsias M, Oto A, Oto O, Pavlovic SU, Piepoli MF, Ristic AD, Rosano GMC, Seggewiss H, Asanin M, Seferovic JP, Ruschitzka F, Celutkiene J, Jaarsma T, Mueller C, Moura B, Hill L, Volterrani M, Lopatin Y, Metra M, Backs J, Mullens W, Chioncel O, de Boer RA, Anker S, Rapezzi C, Coats AJS, Tschope C. Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2019 May;21(5):553-576. doi: 10.1002/ejhf.1461. Epub 2019 Apr 16.

  PMID: 30989768 BACKGROUND

• Rodriguez FH 3rd, Moodie DS, Parekh DR, Franklin WJ, Morales DL, Zafar F, Adams GJ, Friedman RA, Rossano JW. Outcomes of heart failure-related hospitalization in adults with congenital heart disease in the United States. Congenit Heart Dis. 2013 Nov-Dec;8(6):513-9. doi: 10.1111/chd.12019. Epub 2012 Nov 16.

  PMID: 23164196 BACKGROUND

• Lange LG, Schreiner GF. Immune mechanisms of cardiac disease. N Engl J Med. 1994 Apr 21;330(16):1129-35. doi: 10.1056/NEJM199404213301607.

  PMID: 8133856 BACKGROUND

• Matsubara I, Tedo I. [Study on the respiratory failure with cardiac failure--focus on hypoventilation respiratory failure]. Kokyu To Junkan. 1990 Aug;38(8):785-9. Japanese.

  PMID: 2218087 BACKGROUND

• Platz E, Jhund PS, Claggett BL, Pfeffer MA, Swedberg K, Granger CB, Yusuf S, Solomon SD, McMurray JJ. Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. Eur J Heart Fail. 2018 Feb;20(2):295-303. doi: 10.1002/ejhf.901. Epub 2017 Sep 4.

  PMID: 28872259 BACKGROUND

• Ahmed A, Allman RM, Fonarow GC, Love TE, Zannad F, Dell'italia LJ, White M, Gheorghiade M. Incident heart failure hospitalization and subsequent mortality in chronic heart failure: a propensity-matched study. J Card Fail. 2008 Apr;14(3):211-8. doi: 10.1016/j.cardfail.2007.12.001.

  PMID: 18381184 BACKGROUND

• van Deursen VM, Damman K, Hillege HL, van Beek AP, van Veldhuisen DJ, Voors AA. Abnormal liver function in relation to hemodynamic profile in heart failure patients. J Card Fail. 2010 Jan;16(1):84-90. doi: 10.1016/j.cardfail.2009.08.002. Epub 2009 Sep 26.

  PMID: 20123323 BACKGROUND

Related Links

• Heart failure and sepsis: practical recommendations for the optimal management
• Heart Failure in Acute Ischemic Stroke

Biospecimen

Retention: SAMPLES WITHOUT DNA

Blood for liver function, kideny function, CBC, BLOOD CULTURES.

MeSH Terms

Conditions

Cardiomyopathies

Interventions

Echocardiography; Blood Cell Count

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Cardiac Imaging Techniques; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Ultrasonography; Heart Function Tests; Diagnostic Techniques, Cardiovascular; Cell Count; Cytological Techniques; Clinical Laboratory Techniques; Hematologic Tests; Investigative Techniques; Cell Physiological Phenomena; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Study Officials

• Ahmed Mohammed Aly Obied-Allah, Ass.prof.

  Assiut University

  STUDY DIRECTOR

• NoorEldeen Abd-El Azeem M.EL- Hefny, Prof

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

Mohammed Ahmed Abdelhmied, Doctor

CONTACT

01147349160; Abdelhmied22@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 27, 2022
• First Posted: October 5, 2022
• Study Start: September 1, 2023
• Primary Completion: September 1, 2024
• Study Completion: October 1, 2024
• Last Updated: October 6, 2022

Record last verified: 2022-10