Role of MRS in Brain Lesions
Diagnostic Yield of Preoperative Magnetic Resonance Spectroscopy for Solitary Intra-axial Brain Lesion in Comparison to Histopathology
1 other identifier
observational
64
0 countries
N/A
Brief Summary
Aim of the study is evaluation of accuracy of magnetic resonance spectroscopy in differentiation between neoplastic and non neoplastic lesions and determination the type of neoplasm
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Oct 2022
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 30, 2022
CompletedStudy Start
First participant enrolled
October 1, 2022
CompletedFirst Posted
Study publicly available on registry
October 4, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2024
CompletedOctober 4, 2022
September 1, 2022
2 years
September 30, 2022
September 30, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
evaluation of accuracy of magnetic resonance spectroscopy in differentiation between neoplastic and non neoplastic lesions and determination the type of neoplasm
Analysis of the MRS metabolites peaks and test if they can differentiate between neoplastic and non neoplastic lesions and grades of neoplasm by comparison with postoperative histopathology
Baseline
Interventions
It is a tool used to determine the molecular structure of compounds or to detect the compound presence , it provides metabolic information from living brain
Eligibility Criteria
Patients with brain lesions of any age
You may qualify if:
- patients with solitary intraaxial brain lesions
- patients with de novo lesions
- Patient age : any age
You may not qualify if:
- patients with multiple intra-axial brain lesions
- patients with extra-axial brain lesions
- patients with recurrent lesions
- patients receiving chemotherapy or radiotherapy
- patients unfit for surgery
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Ali Ahmed Abd-Elaleem, Lecturer
Assiut University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident doctor
Study Record Dates
First Submitted
September 30, 2022
First Posted
October 4, 2022
Study Start
October 1, 2022
Primary Completion
October 1, 2024
Study Completion
November 1, 2024
Last Updated
October 4, 2022
Record last verified: 2022-09