NCT05562726

Brief Summary

The aim of the present study is to retrospectively record all the successful pregnancies in Greek IBD patients within the last 10 years and prospectively record all the future pregnancies for the next 4 years. Data will be obtained regarding IBD clinical parameters, before, during and after the pregnancy, pregnancy outcomes, delivery mode, lactation and health status of the offspring. Moreover, the management of the pregnant IBD patients in Greece will be analyzed and compared to the European guidelines, in an effort to develop a position statement applicable to the Greek NHS.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2020

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

September 28, 2022

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 3, 2022

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2023

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2024

Completed
Last Updated

February 2, 2023

Status Verified

January 1, 2023

Enrollment Period

4 years

First QC Date

September 28, 2022

Last Update Submit

January 31, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • Data will be obtained regarding IBD clinical parameters, before, during and after the pregnancy.

    the management of the pregnant IBD patients in Greece

    01/01/2020-31/12/2023

  • Data will be obtained regarding IBD pregnancy outcomes and delivery mode.

    the management of the pregnant IBD patients in Greece

    01/01/2020-31/12/2023

  • Data will be obtained regarding lactation and health status of the offspring.

    the management of the pregnant IBD patients in Greece

    01/01/2020-31/12/2023

Eligibility Criteria

Age18 Years+
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsGreek female pregnant IBD women
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Female pregnant IBD patients in Greece

You may qualify if:

  • Patients pregnant with Inflammatory Bowel Disease
  • patients age \>18 years with IBD

You may not qualify if:

  • Termination of pregnancy in the first trimester
  • Miscarriage of pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Alexandra General Hospital Greece

Athens, 11528, Greece

RECRUITING

Related Publications (1)

  • Mahadevan U, Long MD, Kane SV, Roy A, Dubinsky MC, Sands BE, Cohen RD, Chambers CD, Sandborn WJ; Crohn's Colitis Foundation Clinical Research Alliance. Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease. Gastroenterology. 2021 Mar;160(4):1131-1139. doi: 10.1053/j.gastro.2020.11.038. Epub 2020 Nov 21.

MeSH Terms

Conditions

Inflammatory Bowel Diseases

Condition Hierarchy (Ancestors)

GastroenteritisGastrointestinal DiseasesDigestive System DiseasesIntestinal Diseases

Central Study Contacts

Spyridon Michopoulos, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
2 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head of the Gastroenterology Department Alexandra General Hospital Athens Greece

Study Record Dates

First Submitted

September 28, 2022

First Posted

October 3, 2022

Study Start

January 1, 2020

Primary Completion

December 31, 2023

Study Completion

July 1, 2024

Last Updated

February 2, 2023

Record last verified: 2023-01

Locations