Suture Ligation Versus Clipping of Cystic Duct and Artery During Laparoscopic Cholecystectomy

NCT05555810 | Unknown

• 1 other identifier: lclc
• Study Type: interventional
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

The investigators will compare between clipping and ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy. This is the main question that will be discussed in the review.

Conditions

Laparoscopic Cholecystectomy

Outcome Measures

Primary Outcomes (1)

• safety and efficiency of closure of cystic duct and artery after cutting them during laparoscopic cholecystectomy

  The investigators will seek to know the incidence of postoperative complications of laparoscopic cholecystectomy (as signs of biliary leakage as pain, jaundice and raised serum bilirubin level and follow up the drain inserted after doing laparoscopic cholecystectomy) then the investigators will make a comparison between incidence of these complication after closure of cystic duct and artery either by clipping or ligation by sutures. The investigators will try to know rate of advantages disadvantages of each technique also do our best to make strategies for improving efficiency and safety.

  one month

Study Arms (2)

Suture ligation of cystic duct and artery

ACTIVE COMPARATOR

The investigators will ligate cystic duct and artery by traditional sutures during laparoscopic cholecystectomy .

Procedure: clipping or ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy

Application of clips

ACTIVE COMPARATOR

The investigators will put a clips on the cystic duct and artery during laparoscopic cholecystectomy.

Procedure: clipping or ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy

Interventions

clipping or ligation of the cystic duct and the cystic artery in Laparoscopic cholecystectomy PROCEDURE

The investigators will make a comparison between clipping and ligation of cystic duct and cystic artery during Laparoscopic cholecystectomy and trying to know advantages and disadvantages of each technique .

Application of clips; Suture ligation of cystic duct and artery

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• patients with cholecystitis admitted at Assuit University Hospital and planed for lap. cholecystectomy the period of the study

You may not qualify if:

• Any case not candidate for laparoscopic cholecystectomy and we must do it by open technique .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (2)

• van Dijk AH, van Roessel S, de Reuver PR, Boerma D, Boermeester MA, Donkervoort SC. Systematic review of cystic duct closure techniques in relation to prevention of bile duct leakage after laparoscopic cholecystectomy. World J Gastrointest Surg. 2018 Sep 27;10(6):57-69. doi: 10.4240/wjgs.v10.i6.57.

  PMID: 30283606 BACKGROUND

• Singal R, Sharma A, Zaman M. The Safety and Efficacy of Clipless versus Conventional Laparoscopic Cholecystectomy - our Experience in an Indian Rural Center. Maedica (Bucur). 2018 Mar;13(1):34-43.

  PMID: 29868139 BACKGROUND

MeSH Terms

Interventions

Cholecystectomy, Laparoscopic

Intervention Hierarchy (Ancestors)

Cholecystectomy; Biliary Tract Surgical Procedures; Digestive System Surgical Procedures; Surgical Procedures, Operative; Laparoscopy; Endoscopy; Minimally Invasive Surgical Procedures

Study Officials

• Mohamed Korany, PHD

  Assut University

  STUDY DIRECTOR

Central Study Contacts

Morsi Morsi, phd

CONTACT

00201006727303; profmorsy6060@gmail.com

Mostafa Ibrahem, MD

CONTACT

00201095295794; Mostafamahmoud5622@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Model Details: The investigators will secure Cystic duct and artery with traditional sutures(ligation) in a group. In the another group the cystic duct and artery will be put a clips .

Study Record Dates

• First Submitted: September 17, 2022
• First Posted: September 27, 2022
• Study Start: June 1, 2023
• Primary Completion: December 1, 2023
• Study Completion: December 30, 2023
• Last Updated: September 27, 2022

Record last verified: 2022-09