Copenhagen Cohort of Patients With Shoulder Pain
COPAIN
The Copenhagen Cohort of Patients With Shoulder Pain: A Study Investigating Subacromial Impingement and Related Clinical Entities
1 other identifier
observational
218
1 country
1
Brief Summary
The COPAIN study is comprised of three studies; a cross-sectional study (study 1), a prospective study (study 2) and a randomized controlled trial (study 3). Study 3 is described in detail in a separate protocol (the SELECT trial protocol) and is not described in further detail here.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2020
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2020
CompletedFirst Submitted
Initial submission to the registry
September 14, 2022
CompletedFirst Posted
Study publicly available on registry
September 22, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2022
CompletedMarch 8, 2023
March 1, 2023
2.3 years
September 14, 2022
March 7, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Shoulder Pain and Disability Index (SPADI) 3 months after treatment is commenced.
SPADI is a patient-reported outcome measure designed to evaluate shoulder pain and disability. It ranges from 0 (best) to 100 (worst). It has 5 pain items and 8 disability items. The Danish version of SPADI has been found to have good reliability.
3 months
Secondary Outcomes (3)
Oxford Shoulder Score
Baseline, 3, 6 and 12 months
EQ-5D-3L
Baseline, 3, 6 and 12 months
Active shoulder abduction range of motion (AROM)
Baseline, 3, 6 and 12 months
Interventions
The COPAIN study is observational. There is no intervention.
Eligibility Criteria
Adult patients with SIS referred to the place of investigation.
You may not qualify if:
- Terminal illness or severe medical illness (ASA score higher than or equal to 4)
- Systemic musculoskeletal disease
- Inflammatory joint disease (e.g. rheumatoid arthritis)
- Symptomatic cervical spine pathology
- Thoracic outlet syndrome
- Frozen shoulder
- Osteoarthritis of the glenohumeral joint
- Previous surgery, fracture or radiotherapy in the affected shoulder region
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hvidovre Hospital
Hvidovre, 2650, Denmark
Related Publications (1)
Witten A, Clausen MB, Thorborg K, Holmich P, Barfod KW. The Challenge of Diagnosing Patients Presenting With Signs and Symptoms of Subacromial Pain Syndrome: A Descriptive Study of 741 Patients Seen in a Secondary Care Setting. Orthop J Sports Med. 2025 Apr 28;13(4):23259671251332942. doi: 10.1177/23259671251332942. eCollection 2025 Apr.
PMID: 40303319DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Medical Doctor, PhD student
Study Record Dates
First Submitted
September 14, 2022
First Posted
September 22, 2022
Study Start
September 1, 2020
Primary Completion
December 31, 2022
Study Completion
December 31, 2022
Last Updated
March 8, 2023
Record last verified: 2023-03