NCT05547789

Brief Summary

Investigators aimed to assess the macular changes with OCT after uncomplicated phacoemulsification surgery in diabetic patients with non proliferative diabetic retinopathy (NPDR) at the time of surgery and the effect of perioperative and postoperative topical NSAIDS on macular changes .

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2023

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 31, 2022

Completed
21 days until next milestone

First Posted

Study publicly available on registry

September 21, 2022

Completed
5 months until next milestone

Study Start

First participant enrolled

March 1, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2024

Completed
Last Updated

January 10, 2023

Status Verified

September 1, 2022

Enrollment Period

1 year

First QC Date

August 31, 2022

Last Update Submit

January 8, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Macular changes in diabetic patients after phacoemulsification

    Invgatorsiest aimed to examine the macular changes with OCT after uncomplicated phacoemulsification surgery in diabetic patients with non proliferative diabetic retinopathy (NPDR) at the time of surgery and the effect of perioperative and postoperative topical NSAIDS on macular changes .

    baseline

Study Arms (2)

Study group

Drug: non steroidal anti inflammatory drugs

Control group

Interventions

effect of non steroidal anti inflammatory drugs on macular changes

Also known as: optical coherence tomography
Study group

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

preoperatively ,Nonsteroidal anti inflammatory drugs was used for prophylaxis before surgery at the postoperative week 1 we gave the same medication to this group

You may qualify if:

  • Controlled type 2 non proliferative diabetic retinopathy (NPDR) patients. Immature cataract which does not interfere with ocular imaging.

You may not qualify if:

  • Patient with dense cataract or vitreous hemorrhage interfering with measurement of central macular thickness Chronic uveitis Any posterior segment pathology that could affect retinal thickness Patient with complicated cataract surgery.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Assuit University

Asyut, Egypt

Location

Egypt

Asyut, Egypt

Location

Related Publications (1)

  • Furino C, Boscia F, Niro A, D'Addario M, Grassi MO, Saglimbene V, Reibaldi M, Alessio G. DIABETIC MACULAR EDEMA AND CATARACT SURGERY: Phacoemulsification Combined With Dexamethasone Intravitreal Implant Compared With Standard Phacoemulsification. Retina. 2021 May 1;41(5):1102-1109. doi: 10.1097/IAE.0000000000002974.

    PMID: 32897932BACKGROUND

Related Links

MeSH Terms

Conditions

Macular Degeneration

Interventions

Tomography, Optical Coherence

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Tomography, OpticalOptical ImagingDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisTomographyInvestigative Techniques

Study Officials

  • Mohamed T. Abd Elmonaiem, Prof

    Assiut University

    STUDY DIRECTOR
  • Gamal El Dein R. Osman, Ass prof

    Assiut University

    STUDY DIRECTOR
  • Momen M. Aly, Lecture

    Assiut University

    STUDY DIRECTOR

Central Study Contacts

Nermeen M. Ali, Master

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
3 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

August 31, 2022

First Posted

September 21, 2022

Study Start

March 1, 2023

Primary Completion

March 1, 2024

Study Completion

April 1, 2024

Last Updated

January 10, 2023

Record last verified: 2022-09

Locations