Infection Prevention and Control Intervention to Reduce Hospital-acquired Infections

NCT05547373 | Unknown DMC

• 1 other identifier: RCP100737ITDC
• Study Type: interventional
• Target: 192
• Locations: 1 country
• Sites: 1

Brief Summary

Hospital-acquired infections (HAIs) are significant public health issues, especially in low- and middle-income countries (LMICs). Hand hygiene and low-level disinfection of equipment (LLDE) practices among healthcare workers (HCWs) are essential to reduce HAIs. Various effective infection prevention and control (IPC) interventions to reduce HAI incidence have been developed. However, which interventions work effectively in LMICs has not been identified. The investigators aim to develop, pilot, and assess the feasibility and acceptability of an IPC intervention in Cambodia and the Lao People's Democratic Republic (PDR).

Conditions

Hospital-acquired Infections

Keywords

Infection control; Prevention; Hand hygiene; Healthcare workers; Low- and middle-income countries; Asia

Outcome Measures

Primary Outcomes (1)

• Changes in hand hygiene compliance among health workers from baseline to endline

  The investigators will calculate hand hygiene compliance by having the hand hygiene action of alcohol hand rub or hand washing using soap and water divided by the hand hygiene opportunity and multiple with 100.

  At endline (6 months after the intervention started)

Secondary Outcomes (1)

• Perceived feasibility and acceptability of the infection prevention and control intervention among HCWs and stakeholders

  At endline (6 months after the intervention started)

Study Arms (1)

Intervention

EXPERIMENTAL

The investigators will select HCWs from the selected departments at the national hospitals, provincial hospitals, and district referral hospitals to participate in the pilot intervention. The participants will also include representatives from the Communicable Disease Control Department and the Department of Hospital Services of the Ministry of Health, the provincial hospitals, and the district referral hospitals in Cambodia and Lao PDR.

Behavioral: Infection prevention and control (IPC)

Interventions

Infection prevention and control (IPC) BEHAVIORAL

The intervention will be developed by matching behavioral change components identified in the gap analysis stage with the intervention components extracted from a systematic review. The investigators will use the Behavior Change Wheel (BCW) model as a guide to design this infection control prevention and control intervention. In brief, the intervention development processes will follow eight steps based on the BCW. The steps will include defining the problem in behavioral terms, selecting the target behaviors, specifying the target behaviors, identifying what needs to change, identifying intervention functions, identifying policy categories, identifying behavior change techniques, and identifying the mode of delivery.

Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthcare workers working in the selected wards and of chosen hospitals
• Aged 18 years or above
• Working in the selected wards of the chosen hospitals for at least six months
• Being able and agreeing to provide informed consent to participate in the study

You may not qualify if:

• \- Interns and visiting healthcare workers

Sponsors & Collaborators

• National University of Singapore: lead
• Saglik Bilimleri Universitesi: collaborator

Study Sites (1)

Khmer-Soviet Friendship Hospital

Phnom Penh, 12306, Cambodia

RECRUITING

Related Publications (1)

• Oy S, Saing CH, Ung M, Zahari M, Nouhak I, Kim S, Nagashima-Hayashi M, Khuon D, Koy V, Mam S, Sayasone S, Saphonn V, Yi S. Developing an infection prevention and control intervention to reduce hospital-acquired infections in Cambodia and Lao People's Democratic Republic: the HAI-PC study protocol. Front Public Health. 2023 Sep 20;11:1239228. doi: 10.3389/fpubh.2023.1239228. eCollection 2023.

  PMID: 37799162 DERIVED

Central Study Contacts

Sreymom Oy, MSc

CONTACT

+85511867468; smomoy@nus.edu.sg

Chan Hang Saing, PhD

CONTACT

+85512293315; ephchs@nus.edu.sg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 13, 2022
• First Posted: September 21, 2022
• Study Start: April 1, 2023
• Primary Completion: June 30, 2024
• Study Completion: December 31, 2024
• Last Updated: November 14, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)