Effects on the Patellar Tendon After Low-load Blood Flow Restriction Training.

NCT05538494 | Unknown

• 1 other identifier: TFMAON
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective of this research project is to study the transient adaptations that occur in the tendon immediately after the object of training with low loads and blood flow restriction and to compare these adaptations with those derived from training with high loads, in order to thus helping to elucidate the complex existing framework regarding the effects of this training methodology on the tendon.

Conditions

Patellar Tendinitis

Keywords

Patellar tendon; BFRT; vascular occlusion; Ultrasound; blood flow restriction training

Outcome Measures

Primary Outcomes (2)

• To evaluate structural changes in the tendon through the use of ultrasound

  Ultrasound will be used in order to collect the data of the images of each participants. Then, we will asses and compare possible changes in thickness, measured in cm, of each tendon before, after and 24 hour after the intervention.

  Baseline

• To assest the echogenicity of each tendon by using software Fiji-Image J

  A delimited area of 159x20 pixels inside the tendon structure will be selected. Then the program may classified all the pixels of each area on a gray scale of 255, resulting in an histogram of each tendon before, after and 24 hour after the intervention, measured in pixels in the gray scale.

  Baseline

Other Outcomes (1)

• Evaluate the possible presence of micro vascularization of the patellar tendon through the visualization of the tendon structure with the doppler system of the ultrasound.

  Baseline

Study Arms (2)

BFR group

EXPERIMENTAL

Training is applied to this group using low-load exercises with restriction of blood flow.

Other: BFR intervention

High load group

ACTIVE COMPARATOR

A program will be applied to this group of exercise with high loads as a method of treatment

Other: High load intervention

Interventions

BFR intervention OTHER

Training is applied to this group using low-load exercises with restriction of blood flow. Based on the variables used by the major part of the protocols used in studies on the ERFS, the protocol that will be applied to this group will consist of the following parameters. * Training: 1 series of 30 repetitions followed by 3 series of 15 repetitions of squats * Rest between series: Duration of 45 seconds. * Workload: 30% of 1RM. * Cadence: 2 seconds for the concentric phase and 2 seconds for the eccentric phase (2:2). * Cuff pressure: The inflation pressure will be individualized for each individual. A pressure equivalent to 80% of the minimum pressure necessary for the total occlusion of the femoral artery. • Cuff placement: proximal quadriceps.

BFR group

High load intervention OTHER

A program will be applied to this group of exercise with high loads as a method of treatment in which the following will be applied parameters: * Training: 4 series of 12 repetitions of squats. * Rest between series: Duration 2 minutes. * Workload: 70% of 1RM.

High load group

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Physically active population (physical activity between 1 and 3 weekly sessions). With the final purpose to adjust the results to normality and refer to a general population.
• Subjects who have received the information sheet and have given their consent informed to participate in the study.

You may not qualify if:

• People who reproduce pain or symptomatology to the execution of the exercise of the treatment.
• People who have had symptoms in the last 2 months in the region below patellar
• Present musculoskeletal injuries or inability to perform the protocol experimental.
• Individuals with a training frequency equal to or greater than 5 sessions per week or that present a RM equal to or greater than 110kg. Since they do not fit a population and may affect the homogeneity of the sample.

Sponsors & Collaborators

• University of Alcala: lead

Study Sites (1)

University of Alcala

Alcalá de Henares, Madrid, 28805, Spain

Location

Related Publications (25)

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  BACKGROUND

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  BACKGROUND

• Risch L, Mayer F, Cassel M. Doppler Flow Response Following Running Exercise Differs Between Healthy and Tendinopathic Achilles Tendons. Front Physiol. 2021 Mar 23;12:650507. doi: 10.3389/fphys.2021.650507. eCollection 2021.

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• Moisés Picón Martínez. Efectos agudos del entrenamiento con restricción del flujo sanguíneo sobre el tendón, la respuesta cardiovascular y la respuesta muscular Universitat d'Alacant - Universidad de Alicante; 2018.

  BACKGROUND

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  PMID: 30246795 BACKGROUND

Study Officials

• Néstro Ruíz Alberto, Physio

  University of Alcala

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: double blinding between investigator and study participants
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Model Details: The first group, which we will call the "BFR group", will be trained using low-load exercises with blood flow restriction. To the second group, which we will call "high load group", an exercise program with high loads will be applied.

Study Record Dates

• First Submitted: August 26, 2022
• First Posted: September 14, 2022
• Study Start: February 20, 2021
• Primary Completion: June 13, 2022
• Study Completion: September 10, 2022
• Last Updated: September 14, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)