SMS Reminders to Strengthen Demand for HPV Vaccination in Georgia
Design, Test and Evaluate Behavioural Insights Interventions to Strengthen Demand for Immunisation in Georgia
1 other identifier
interventional
55,176
0 countries
N/A
Brief Summary
It is possible that achieving adequate HPV vaccination coverage will allow cervical cancer to be virtually eliminated. This is a priority for Georgia, where the burden of mortality and morbidity from cervical cancer is high and the yearly prevalence of cervical cancer is 14.5 per 100,000 population. The objective of the intervention evaluated is to increase the uptake of the 1st dose of the HPV vaccination in Georgia. The intervention aims to achieve this by providing a SMS reminder informed by behavioural insights (BI) to remind caregivers of girls between 10-12 years that their daughter is due the first dose of her HPV vaccination, share information about the vaccine, and encourage them to book an appointment to receive the vaccination. Four different SMS messages will be compared to no SMS message. The evaluation will be a 5-arm randomised controlled trial (RCT) which aims to answer the research question: Does each of the designed BI-informed SMS reminders increase the uptake of the first dose of the HPV vaccination among eligible girls in Georgia, compared to no reminder? Our hypothesis is that SMS reminders will increase the uptake of HPV vaccination.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Sep 2022
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 8, 2022
CompletedFirst Posted
Study publicly available on registry
September 13, 2022
CompletedStudy Start
First participant enrolled
September 13, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 12, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
November 12, 2022
CompletedSeptember 13, 2022
September 1, 2022
2 months
September 8, 2022
September 8, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
HPV vaccination status
1st dose HPV vaccination status of the caregiver's daughter
At 60 days after receiving the SMS reminder
Study Arms (5)
No SMS reminder
NO INTERVENTIONThis group will receive no reminder
Short SMS with no additional information
EXPERIMENTALCaregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Contact your family doctor today to arrange an appointment."
Short SMS + NCDC link
EXPERIMENTALCaregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"
SMS with "reserved for her" framing + NCDC link
EXPERIMENTALCaregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. Her vaccine is reserved at the policlinic. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"
SMS with safety information + NCDC link
EXPERIMENTALCaregivers of girls eligible to receive the HPV vaccination in this group will receive an SMS reminder that states: "As per national immunization calendar your daughter is due her free human papilloma virus vaccine, which will protect her against cervical cancer. The vaccine has been given safely to more than 118 million girls worldwide. Contact your family doctor today to arrange an appointment. More information on the official NCDC website"
Interventions
A BI-informed SMS reminder to remind caregivers of girls between 10-12 years that their daughter is due the first dose of her HPV vaccination and share information about the vaccine.
Eligibility Criteria
You may qualify if:
- Girls
- Aged 10-12 years
- Not yet received any doses of the HPV vaccine
- With a caregiver's mobile phone number in the e-health system.
You may not qualify if:
- Boys
- Girls aged less than 10 or more than 12 years
- Girls with no caregiver phone number in the e-health system
- Girls who have received 1 or 2 doses of the HPV vaccine
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The Behavioural Insights Teamlead
- UNICEFcollaborator
- National Center for Disease Control and Public Health, Georgiacollaborator
- Information Technology Agency, Georgiacollaborator
Related Publications (1)
Daly N, Merriam S, Tagliaferri G, Tomsa S, Bianco VM, Gamgebeli L, Lortkipanidze N. Effectiveness of SMS reminders to increase demand for HPV immunisation: a randomised controlled trial in Georgia. BMJ Open. 2025 Nov 13;15(11):e087080. doi: 10.1136/bmjopen-2024-087080.
PMID: 41248345DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Hannah Behrendt
Behavioural Insights Team
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 8, 2022
First Posted
September 13, 2022
Study Start
September 13, 2022
Primary Completion
November 12, 2022
Study Completion
November 12, 2022
Last Updated
September 13, 2022
Record last verified: 2022-09
Data Sharing
- IPD Sharing
- Will not share
No individual data will be shared from the e-health modules of the National Center for Disease Control and Public Health of Georgia and Information Technology Agency. All data shared will be anonymised for analysis and aggregated for reporting, there is no risk of participant identification. Data will include HPV vaccination status, the version of the SMS reminder received, and age. The data will not include information on patients' names, addresses, location, ethnicity, phone numbers, or any information on medical conditions.