Validation of the Chinese Version of Oxford Depression Questionnaire

NCT05535270 | Completed DMC

• 1 other identifier: IIT20220240B-R1
• Study Type: observational
• Target: 272
• Locations: 1 country
• Sites: 1

Brief Summary

Mood disorders are a group of psychiatric disorders that can affect a person's mood, energy, and motivation. Emotional blunting has been observed in clinical practice in patients with mood disorders. Emotional blunting has a negative impact on patients' overall treatment and leads to poorer adherence. The Oxford Depression Questionnaire (ODQ) is a measuring instrument of emotional blunting. The ODQ is expected to be a scientifically valid tool for detecting emotional blunting. The ODQ has high construct validity and internal reliability. However, no scientific validity studies have been conducted on ODQ in Chinese population. Therefore, this study is intended to investigate the reliability and validity of the ODQ in Chinese patients with mood disorders.

Conditions

Mood Disorders; Emotional Blunting

Outcome Measures

Primary Outcomes (1)

• Oxford Depression Questionnaire (ODQ)

  To analyze reliability and validity of the ODQ.

  baseline

Secondary Outcomes (3)

• Beck Depression Inventory-II (BDI-II)

  baseline

• Montgomery-Asberg Depression Rating Scale (MADRS)

  baseline

• Oxford Depression Questionnaire (ODQ)

  2 weeks after baseline

Study Arms (2)

Mood Disorder patients

The participants completed a demographic questionnaire, the self-report Oxford Depression Questionnaire (ODQ-C), the Beck Depression Inventory-II(BDI-II), and the Montgomery-Asberg Depression Rating Scale (MADRS).

Diagnostic Test: Oxford Depression Questionnaire (ODQ)

Healthy Controls

The participants completed a demographic questionnaire, Patient Health Questionnaire - 9(PHQ-9), and the first two sections of Oxford Depression Questionnaire (ODQ-20).

Diagnostic Test: Oxford Depression Questionnaire (ODQ)

Interventions

Oxford Depression Questionnaire (ODQ) DIAGNOSTIC_TEST

The Oxford Depression Questionnaire (ODQ)is a patient-centered questionnaire. The scale contains three sections: i) the patient's experience in the past week; ii) the patient's experience before the illness worsened, and iii) the patient's emotional feelings about receiving antidepressant treatment. The 26-item questionnaire contains four dimensions of "emotional blunting": not caring (NC), emotional detachment from others (ED), reduction in positive emotions (RP), and general reduction in emotions (GR). Patients not taking antidepressants were only required to rate the first two sections .

Healthy Controls; Mood Disorder patients

Eligibility Criteria

• Age: 13 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants with mood disorders are recruited as outpatients or inpatients with the First Affiliated Hospital of Zhejiang University, School of Medicine.

You may qualify if:

• \) both biological parents were Han Chinese; 2) currently diagnosed with major depressive disorder or bipolar disorder according to the Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; 3) aged 13-65 years; 4) can complete the self-assessment questionnaires.

You may not qualify if:

• \) currently diagnosed with neurological diseases or other major psychiatric disorders, e.g., schizophrenia, cognitive impairment, substance abuse; 2) diagnosed with severe somatic illnesses, such as diabetes and cardiovascular diseases;

Sponsors & Collaborators

• First Affiliated Hospital of Zhejiang University: lead

Study Sites (1)

Department of Psychiatry, First Affiliated Hospital of Zhejiang University

Hangzhou, Zhejiang, 310000, China

Location

MeSH Terms

Conditions

Mood Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of Department of Psychiatry, First Affiliated Hospital of Zhejiang University

Study Record Dates

• First Submitted: September 6, 2022
• First Posted: September 10, 2022
• Study Start: January 1, 2022
• Primary Completion: June 1, 2023
• Study Completion: June 30, 2023
• Last Updated: September 15, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)