NCT05524467

Brief Summary

Vifor International Inc. is seeking real-world evidence (RWE) to better understand the epidemiology, patient characteristics, and management of CKD-aP in the real-world clinical setting.

Trial Health

93
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,100

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2023

Shorter than P25 for all trials

Geographic Reach
7 countries

94 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 29, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 1, 2022

Completed
5 months until next milestone

Study Start

First participant enrolled

February 2, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2024

Completed
Last Updated

July 9, 2024

Status Verified

December 1, 2023

Enrollment Period

12 months

First QC Date

August 29, 2022

Last Update Submit

July 8, 2024

Conditions

Keywords

CKDCKD-APCKD associated pruritus

Outcome Measures

Primary Outcomes (1)

  • Prevalence of CKD-aP in HD patients

    Percentage (%)

    A 7-month study timeline

Secondary Outcomes (1)

  • The prevalence of CKD-aP by severity

    A 7-month study timeline

Study Arms (1)

Haemodialysis Patients

Only one data collection timepoint per patient is planned. Eligible and consenting patients will be asked to complete several PROs and one questionnaire, and their respective medical charts will be assessed retrospectively

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The CENSUS-EU represents a cross-sectional study design of a representative selection of patients undergoing HD at 113 large dialysis centres across 7 countries in Europe. Prot. v.2.0, 9 May 2023

You may qualify if:

  • Male or female adult patients with CKD (≥18 years) receiving HD for at least 3 months prior to signing informed consent
  • Signed informed consent
  • Able and willing to fill in questionnaires

You may not qualify if:

  • Patients performing HD at home or both home and centre

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (94)

1113

Aschaffenburg, Germany

Location

1011

Balingen, Germany

Location

1007

Braunschweig, Germany

Location

1016

Einbeck, Germany

Location

1012

Eisenach, Germany

Location

1043

Flensburg, Germany

Location

1048

Freiburg im Breisgau, Germany

Location

1049

Freiburg im Breisgau, Germany

Location

1046

Hanover, Germany

Location

1001

Herne, Germany

Location

1035

Kiel, Germany

Location

1111

Leipzig, Germany

Location

1013

Mainz, Germany

Location

1047

Saalfeld, Germany

Location

1053

Sömmerda, Germany

Location

1044

Witten, Germany

Location

1051

Wuppertal, Germany

Location

4027

Acquaviva delle Fonti, Italy

Location

4015

Bari, Italy

Location

4010

Civitavecchia, Italy

Location

4001

Florence, Italy

Location

4005

Lecce, Italy

Location

4016

L’Aquila, Italy

Location

4008

Macerata, Italy

Location

4023

Mestre, Italy

Location

4006

Milan, Italy

Location

4018

Milan, Italy

Location

4021

Milan, Italy

Location

4011

Modena, Italy

Location

4009

Monza, Italy

Location

4003

Palermo, Italy

Location

4017

Parma, Italy

Location

4006

Pavia, Italy

Location

4028

Pisa, Italy

Location

4002

Pistoia, Italy

Location

4026

Reggio Calabria, Italy

Location

4014

Roma, Italy

Location

4024

Rome, Italy

Location

4022

Treviso, Italy

Location

4030

Trieste, Italy

Location

4012

Verona, Italy

Location

4025

Viterbo, Italy

Location

5014

Cascais, Portugal

Location

5001

Faro, Portugal

Location

5013

Gandra, Portugal

Location

5011

Gondomar, Portugal

Location

5006

Leiria, Portugal

Location

5008

Porto, Portugal

Location

5002

Sacavém, Portugal

Location

3009

Palma de Mallorca, Mallorca, Spain

Location

3006

Almería, Spain

Location

3005

Barcelona, Spain

Location

3011

Barcelona, Spain

Location

3012

Barcelona, Spain

Location

3026

Barcelona, Spain

Location

3002

Benidorm, Spain

Location

3008

Cadiz, Spain

Location

3001

Gijón, Spain

Location

3018

Granada, Spain

Location

3025

Jaén, Spain

Location

3020

Las Palmas, Spain

Location

3021

León, Spain

Location

3015

Madrid, Spain

Location

3016

Madrid, Spain

Location

3022

Madrid, Spain

Location

3024

Madrid, Spain

Location

3017

Pamplona, Spain

Location

3013

Santander, Spain

Location

3007

Seville, Spain

Location

3023

Seville, Spain

Location

3010

Terrassa, Spain

Location

3003

Valencia, Spain

Location

3004

Valencia, Spain

Location

3027

Valencia, Spain

Location

6008

Linköping, Sweden

Location

6007

Malmo, Sweden

Location

6005

Norrköping, Sweden

Location

6004

Örebro, Sweden

Location

6001

Stockholm, Sweden

Location

6003

Trollhättan, Sweden

Location

6006

Umeå, Sweden

Location

6002

Uppsala, Sweden

Location

2009

Baden, Switzerland

Location

2001

Bern, Switzerland

Location

2002

Frauenfeld, Switzerland

Location

2004

Lugano, Switzerland

Location

2003

Zurich, Switzerland

Location

7002

Bradford, United Kingdom

Location

7003

Hull, United Kingdom

Location

7001

Leicester, United Kingdom

Location

7006

London, United Kingdom

Location

7007

London, United Kingdom

Location

7005

Nottingham, United Kingdom

Location

7004

Sheffield, United Kingdom

Location

Study Officials

  • James Burton, Prof.

    University of Leicester Leicester, United Kingdom

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 29, 2022

First Posted

September 1, 2022

Study Start

February 2, 2023

Primary Completion

January 31, 2024

Study Completion

January 31, 2024

Last Updated

July 9, 2024

Record last verified: 2023-12

Data Sharing

IPD Sharing
Will share

Anonymized individual patient level data will be provided in a secure access environment upon approval of a research proposal and a signed data sharing agreement.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data can be requested 6 months after the primary publication and approval of the indication studied in the US and European Union (EU), whichever is later. Data will be indefinitely available for requesting
Access Criteria
A research proposal must be approved by an independent review panel and the study sponsor and researchers must sign a data sharing agreement.

Locations