NCT05522114

Brief Summary

This study is designed to evaluate the accuracy of planned needle position using patient specific guide during TMJ superior joint space injection.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 19, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 3, 2022

Completed
19 days until next milestone

Study Completion

Last participant's last visit for all outcomes

August 22, 2022

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

August 26, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 30, 2022

Completed
Last Updated

August 30, 2022

Status Verified

August 1, 2022

Enrollment Period

4 months

First QC Date

August 26, 2022

Last Update Submit

August 29, 2022

Conditions

Keywords

virtual planning3D printingTMD

Outcome Measures

Primary Outcomes (3)

  • Angle of deviation

    The angle (°) between the planned and actual needle measured.

    1 month

  • Vertical displacement of needle tip

    The vertical displacement of the actual needle tip in comparison to the planned one (mm).

    1 month

  • Overall needle tip dislocation

    The distance between the planned and actual needle tips (mm).

    1 month

Study Arms (1)

Patient specific guided injection

EXPERIMENTAL

Patients treated with HA injection in TMJ using PSG and the accuracy evaluated using MSCT.

Procedure: TMJ injection using patient specific guide

Interventions

Prefabricated patient specific guide used to guide the needle into the superior joint space of TMJ while real time MSCT evaluate the accuracy of needle position. Sodium hyaloronate injected within the superior joint space.

Patient specific guided injection

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Patients diagnosed with intra-articular TMJ disorder according to Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD).
  • Patients who would not respond to conservative treatment as the first line of treatment.

You may not qualify if:

  • Lactating, pregnant or planning pregnancy women.
  • Known hypersensitivity to hyaluronic acid or clear biocompatible photopolymer resin.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry, Al-Azhar University.

Cairo, 11884, Egypt

Location

Study Officials

  • AbdElKader A Hyder, MSc

    Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Al-Azhar University

    PRINCIPAL INVESTIGATOR
  • Wael A ElMohandes, PhD

    Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Al-Azhar University

    STUDY DIRECTOR
  • Bahaa El-Din A Tawfik, PhD

    Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Al-Azhar University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

August 26, 2022

First Posted

August 30, 2022

Study Start

April 19, 2022

Primary Completion

August 3, 2022

Study Completion

August 22, 2022

Last Updated

August 30, 2022

Record last verified: 2022-08

Locations